Metformin diminishes the unfavourable impact of Nrf2 in breast cancer patients with type 2 diabetes
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Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a major regulator of the oxidative stress response and it is negatively regulated by Kelch-like ECH-associated protein 1 (Keap1). The Keap1-Nrf2 axis has a fundamental role in carcinogenesis. In previous st... ...
