Citomegalovirus Serology and Response to Autologous Haematopoietic Stem Cell Transplantation in Persons With Multiple Sclerosis [0.03%]
多发性硬化患者巨细胞病毒血清学与自体造血干细胞移植应答的关系
Luis Enrique Hamilton-Avilés,Moisés Manuel Gallardo-Pérez,Miranda Melgar-de-la-Paz et al.
Luis Enrique Hamilton-Avilés et al.
Multiple sclerosis (MS) is a prevalent autoimmune disease with increasing incidence in certain populations, and autologous haematopoietic stem cell transplantation (aHSCT) represents an important therapeutic option. Cytomegalovirus (CMV) ha...
Methotrexate Exhibits a Dual Role in Regulation of CD4+ T Follicular Helper (Tfh) Cell Differentiation and Activity [0.03%]
甲氨蝶呤在CD4⁺滤泡辅助性T细胞分化及功能中的双重作用研究
Sayan Chakraborty,Poulomi Khamaru,Altamas Hossain Daptary et al.
Sayan Chakraborty et al.
Methotrexate (MTX) is one of the most prevalent drugs used in the treatment of autoimmune disorders as it has an established role in preventing T and B cell proliferation which reduces the severity of autoimmunity. However, MTX in combinati...
Granulomatous and Lymphocytic Interstitial Lung Disease in Hyper-IgM Syndrome [0.03%]
高IgM综合征的肉芽肿性和淋巴细胞性间质性肺病
Muhammed Aydin,Sezin Aydemir,Zeynep Meric et al.
Muhammed Aydin et al.
The Impact of Complement Factor H-Related Protein Gene Deletions on Kidney Transplantation [0.03%]
补体因子H相关蛋白基因缺失对肾移植的影响
Markkinen Salla,Lokki A Inkeri,Helanterä Ilkka et al.
Markkinen Salla et al.
We recently reported that a homozygous deletion in the complement factor H-related (CFHR) locus predisposed kidney transplant patients to rejection. As donors carried intact genes, the susceptibility may have resulted from an alloimmune rea...
Diagnostic Performance of Three Serological Assays in Myasthenia Gravis: A Prospective Multicentre Study [0.03%]
三种自身抗体检测方法在重症肌无力诊断中的临床价值:一项多中心研究
Laura Cuomo,Laura De Giglio,Maria Antonietta Isgrò et al.
Laura Cuomo et al.
Anti-acetylcholine receptor (AChR) and anti-muscle-specific tyrosine kinase (MuSK) autoantibody detection is crucial in the diagnosis and choice of treatment of myasthenia gravis (MG). We conducted a multicentre prospective study comparing ...
Comparative Study
Scandinavian journal of immunology. 2025 Dec;102(6):e70072. DOI:10.1111/sji.70072 2025
Common Variable Immune Deficiency Disorders (CVID) in the Indigenous Māori of Aotearoa (New Zealand) Are Associated With a High Prevalence of Bronchiectasis and Complete IgA Deficiency [0.03%]
毛里塔尼亚土著毛利人的常见可变免疫缺陷综合症(CVID)与支气管扩张和完全性分泌型免疫球蛋白A(SIgA)缺乏高发相关
Rohan Ameratunga,Catherine A Byrnes,Anthony Jordan et al.
Rohan Ameratunga et al.
The New Zealand (NZ) Common Variable Immunodeficiency Disorders (CVID) study (NZCS) is a long-term prospective cohort study, which seeks to better understand the proximal causes and sequelae of CVID. Patients were accepted to the NZCS if th...
Oral and Skin Sensitisation to Peanut Show Different Immunological Features in Brown Norway Rats [0.03%]
棕挪威大鼠的花生口腔和皮肤致敏具有不同的免疫特征
Tiffany K S Sztuk,Jeppe M Larsen,Neil M Rigby et al.
Tiffany K S Sztuk et al.
Food allergy may develop after both oral and skin exposure to food allergens. Identifying immunological features associated with the sensitisation route is important for understanding the extent to which patients are sensitised through the ...
Mycobacterial Infections in Wiskott Aldrich Syndrome: A Predisposition or Coincidence? [0.03%]
Wiskott-Aldrich综合征患者中结核分枝杆菌感染的易感性或偶然性?
Dev Desai,Loganathan Sathish Kumar,Simar Rajan Singh et al.
Dev Desai et al.
Skin-Homing Potential of Peripheral Immune Cells From Psoriasis Patients and the Effects of LL-37 on Their Secretion of Chemokines During Psoriasis-Mimicking Stimulation [0.03%]
银屑病患者外周免疫细胞向皮肤迁移的潜能及其分化过程中LL-37对细胞趋化因子分泌的影响
Hildur Sigurgrímsdóttir,Jenna Huld Eysteinsdóttir,Árni Kjalar Kristjánsson et al.
Hildur Sigurgrímsdóttir et al.
Psoriasis is an autoimmune disease of the skin with keratinocyte hyperproliferation and increased skin homing of immune cells. LL-37 is an antimicrobial peptide present at a high level in psoriasis patients. It is thought to participate in ...
Expansion of Myeloid-Derived Suppressor Cells and Lymphocyte Apoptosis Beyond B-Cell Deficiency in X-Linked Agammaglobulinemia [0.03%]
X连锁无丙种球蛋白血症中髓源性抑制细胞的扩增和淋巴细胞凋亡超出了B细胞缺陷范围
Ayca Ceylan,Ilknur Kulhas Celik,Sevgi Keles et al.
Ayca Ceylan et al.
X-linked agammaglobulinemia (XLA) is caused by Bruton tyrosine kinase gene mutations, leading to B-cell deficiency. This study aimed to investigate myeloid-derived suppressor cells (MDSCs) frequency, lymphocyte apoptosis and clinical signif...