Photoelectrocatalytic XAT strategy for the generation of alkyl radicals to synthesize alkylated 3-CF3-2-oxindoles [0.03%]
光解催化XAT策略生成烷基自由基合成烷基化3-CF3-2-恶吲哚化合物
Qinhui Wan,Xia-Die Wu,Fei-Fei Xu et al.
Qinhui Wan et al.
An organocatalyzed photoelectrochemical strategy for the generation of alkyl radicals from alkyl bromides and iodides through a halogen atom transfer (XAT) process has been developed. These alkyl radicals are used in radical tandem cyclizat...
Venkatakrishnan Balasubramanian,Sai Kishore Butti,Nettem V Choudary et al.
Venkatakrishnan Balasubramanian et al.
This highlight provides an accessible overview of hydrogen production technologies, structured around a widely adopted color coded typology: grey, blue, green, yellow, pink, turquoise, and white, based on their technoeconomic and environmen...
Toward understanding and development of the three-dimensional atomic structures of supported metal catalysts [0.03%]
从认识和开发负载型金属催化剂的三维原子结构出发
Junya Ohyama
Junya Ohyama
Understanding of supported metal catalysts, which are indispensable for numerous practical chemical processes including chemical production, environmental purification, and power generation, has deepened alongside advances in analytical tec...
Heme-based catalysis for sustainable carbene transfer chemistry: computational mechanistic investigations [0.03%]
基于血红素的催化体系用于可持续卡宾转移反应的理论研究
Vrinda Modi,Yong Zhang
Vrinda Modi
Recently, engineered heme proteins have been developed as excellent catalysts for carbene transfer reactions to facilitate sustainable chemical synthesis. Computational mechanistic investigations provide significant insights into the unders...
A sticky end-driven PAM-free RPA-CRISPR/Cas12a dual amplification system for ultrasensitive detection of KRAS G12C [0.03%]
一种基于CRISPR/Cas12a的无PAM要求的粘性末端驱动RPA双重扩增系统实现KRAS G12C突变的超灵敏检测
Liyuan Deng,Xinyu He,Shiying Zhou et al.
Liyuan Deng et al.
Herein, a fluorescent biosensing platform was constructed for KRAS G12C single base mutation detection by CRISPR/Cas12a-coupled RPA without the PAM site. The KRAS G12C gene sequence was cleaved into double-stranded DNA containing a sticky e...
Recent advances in fluorescent glycoconjugate probes for biosensing, bioimaging and targeted photodynamic therapy [0.03%]
用于生物传感、生物影像和靶向光动力治疗的荧光糖缀合物探针最新研究进展
Hai-Hao Han,Xi-Le Hu,Xiao-Peng He
Hai-Hao Han
Fluorescent glycoconjugate probes have emerged as innovative tools for biomedical research, helping to delineate the mechanistic roles of sugars in biological and pathological events. This feature article reviews the recent advances in the ...
Harnessing conserved G-quadruplexes for fluorescence detection of Mycobacterium tuberculosis [0.03%]
利用保守的G-四链体检测荧光分光法检测结核杆菌
Vasudhar Bhat S V,Sumon Pratihar,Krithi K Bhagavath et al.
Vasudhar Bhat S V et al.
We report the fluorescence detection of the conserved G-quadruplex (GQ) motif in Mycobacterium tuberculosis (MTB) DNA, ensuring high specificity with minimal interference from human and non-MTB DNA sequences. The duplex-to-GQ reliable confo...
Constructing stable solid electrolyte interfaces and facilitating Li transport via an electrolyte additive for lithium metal batteries [0.03%]
通过电解液添加剂构建稳定的固态电解质界面并促进锂金属电池中的锂传输
Meng Li,Zeren Zhou,Qixian Zhang et al.
Meng Li et al.
Herein, we propose N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) as an electrolyte additive. MSTFA enters the solvation structure and participates in the formation of a stable SEI/CEI. An electrolyte containing MSTFA makes the Li‖...
Fe(III)/NaBD4-mediated regioselective deuteration/cyclization of 1,7-enynes and 1,7-dienes [0.03%]
Fe(III)/NaBD4介导的1,7-炔烯和1,7-二烯的选择氘化/环化反应
Guiling Li,Mengshuang Guo,Yijia Zhang et al.
Guiling Li et al.
We developed an Fe(III)/NaBD4-mediated method for regioselective deuteration/cyclization of 1,7-enynes and 1,7-dienes, yielding deuterated dihydroquinolin-2(1H)-ones and benzo[b]azepinones. Distinct regioselectivity was observed: deuterium ...
Microwave-assisted Pd-catalyzed B-N cross-coupling for efficient functionalization of the carbaborate [CB11H12] [0.03%]
微波促进的Pd催化B-N交叉偶联反应实现卡宾碳硼烷([CB11H12]-)的高效官能化
Yujie Jin,Lianyu Chen,Chennuo Jiang et al.
Yujie Jin et al.
A highly efficient Pd-catalyzed B-N coupling of [12-I-CB11H11]- with amides and amines has been developed, enabling efficient access to nitrogen-functionalized carbaborate derivatives. The method proceeds under mild conditions with broad su...