HFIP-Promoted [18F] trifluoromethylation via iodofluorination of gem-difluoroalkenes
{{output}}
Herein, we report a novel hydrogen-bond-assisted radiofluorination strategy for the trifluoromethylation of gem-difluoroalkenes, utilizing NIS as the activator and HFIP as the essential solvent to facilitate key hydrogen-bonding interactions. This method demon... ...