Statistically verified methods for determining predictors of development of arterial hypertension depending on endothelial nitric oxide synthase T786C gene promoter polymorphism using lipid profile indicators [0.03%]
基于血脂指标的端粒酶基因启动子多态性依赖的高血压预测因子的统计验证方法
Svitlana Pidruchna,Volodimir Shmanko,Roman Hnizdyukh et al.
Svitlana Pidruchna et al.
Objective. Polymorphism investigation of T786C gene promoter of endothelial nitric oxide synthase (eNOS/NOS3) in the arterial hypertension is a promising field for determining the relationship between heredity, hypertension, and dyslipidemi...
Tomas Havranek,Zuzana Bacova,Jan Bakos
Tomas Havranek
Oxytocin plays an important role in brain development and is associated with various neurotransmitter systems in the brain. Abnormalities in the production, secretion, and distribution of oxytocin in the brain, at least during some stages o...
Association of lipid profile and obesity in patients with polycystic ovary syndrome [0.03%]
多囊卵巢综合征患者的血脂谱与肥胖关系分析
Sadaf Parveen,Saba Khan,Mohammad Mustufa Khan et al.
Sadaf Parveen et al.
Objective. Abnormal lipid profile and obesity increase the risk of polycystic ovary syndrome (PCOS). PCOS patients may have a greater risk of infertility, metabolic syndrome (MetS) and cardiovascular disease (CVD) due to abnormal lipid prof...
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells [0.03%]
抑制信号蛋白ERN1可增加U87MG胶质母细胞瘤细胞中丝氨酸合成基因表达对葡萄糖和谷氨酰胺剥夺的敏感性
Oleksandr H Minchenko,Myroslava Y Sliusar,Olena O Khita et al.
Oleksandr H Minchenko et al.
Objective. Glucose and glutamine supply as well as serine synthesis and endoplasmic reticulum (ER) stress are important factors of glioblastoma growth. Previous studies showed that the knockdown of ERN1 (ER to nucleus signaling 1) suppresse...
Persistent chronic calcific pancreatitis with intraductal calculi associated with secondary diabetes mellitus type 3 and diabetic ketoacidosis - A case report [0.03%]
慢性胰管结石性胰腺炎伴2型糖尿病及糖尿病酮症酸中毒的病例报告
Gurusha Bahl,Dinesh K Upadhyay,Madhumati Varma et al.
Gurusha Bahl et al.
Diabetes mellitus type 3 refers to diabetes secondary to an existing disease or condition of the exocrine pancreas and is an uncommon cause of diabetes occurring due to pancreatogenic pathology. It accounts for 15-20% of diabetic patients i...
The relationship between the tumor and its innervation: historical, methodical, morphological, and functional assessments - A minireview [0.03%]
肿瘤及其神经支配之间的关系：历史、方法、形态和功能评估的简要综述
Filip Blasko,Lubica Horvathova
Filip Blasko
The acceptance of the tumor as a non-isolated structure within the organism has opened a space for the study of a wide spectrum of potential direct and indirect interactions, not only between the tumor tissue and its vicinity, but also betw...
Relationships of apolipoprotein E genotypes with a cluster of seven in persons with type 2 diabetes [0.03%]
载脂蛋白E基因型与2型糖尿病患者的七项指标异常之间的关系
Douglas E Barre,Kazimiera A Mizier-Barre,Odette Griscti et al.
Douglas E Barre et al.
Objective.: The objective of the study was to determine if there would be statistically significant differences or trends among apolipoprotein E genotypes (2/2, 2/3, 2/4, 3/3, 3/4, and 4/4) for each member of the cluster ...
Advanced glycation end products of dietary origin and their association with inflammation in diabetes - A minireview [0.03%]
膳食晚期糖基化终末产物及其与糖尿病炎症的关系-一综述性文章
Adriana Pedreanez,Jorge Robalino,Diego Tene et al.
Adriana Pedreanez et al.
Advanced glycation end products (AGEs) are a diverse group of compounds that are formed as a result of the non-enzymatic reaction between a reducing sugar such as glucose and the free NH2 groups of an amino acid in a protein or other biomol...
ERN1 knockdown modifies the hypoxic regulation of homeobox gene expression in U87MG glioblastoma cells [0.03%]
ERN1敲低可改变U87MG胶质母细胞瘤细胞在缺氧条件下同源结构域基因表达的调节作用
Daria A Krasnytska,Olena O Khita,Yuliia M Viletska et al.
Daria A Krasnytska et al.
Objective.: Homeobox genes play an important role in health and disease including oncogenesis. The present investigation aimed to study ERN1-dependent hypoxic regulation of the expression of genes encoding homeobox protei...
Potential of medicinal plants to ameliorate neovascularization activities in diabetes: A systematic review [0.03%]
植物药调节糖尿病新生血管活动的潜力系统性回顾研究
Phaik Har Yong,Shin Yee New,Meram Azzani et al.
Phaik Har Yong et al.
Hyperglycemia in diabetes mediates the release of angiogenic factors, oxidative stress, hypoxia, and inflammation, which in turn stimulate angiogenesis. Excessive angiogenesis can cause diabetic retinopathy, diabetic neuropathy, and diabeti...