Unique hyaluronan structure of expanded oocyte-cumulus extracellular matrix in ovarian follicles
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In preovulatory follicles, after the endogenous gonadotropin surge, the oocyte-cumulus complexes (OCCs) produce hyaluronan (HA) in a process called "cumulus expansion". During this process, the heavy chains (HCs) of the serum-derived inter-alpha-trypsin inhibi... ...
