One genotype with a myriad of phenotypes: A family with multiple endocrine neoplasia [0.03%]
一个基因型与多种表现型：多发性内分泌肿瘤家系一例
Oumeyma Trimeche,Fatma Mnif,Fatma Abdelhedi et al.
Oumeyma Trimeche et al.
Objective. Multiple endocrine neoplasia type 1 (MEN1) is a very rare genetic disorder characterized by an autosomal dominant inheritance. We aim through this case series to delineate the wide spectrum of its clinical features. Methods. In t...
Modulation of appetite- and metabolism-regulating hormones after bariatric embolization, sleeve gastrectomy, and gastric plication [0.03%]
胃脏栓塞、袖状胃切除术和胃折叠术后调节食欲和代谢调节激素的作用
Andrii Prodan,Ihor Dzubanovsky,Yaroslav Ihorovych Havrysh
Andrii Prodan
Objective. The obesity is associated with profound disturbances in appetite-regulating and metabolic hormones including ghrelin, leptin, adiponectin, resistin, and insulin. Bariatric arterial embolization (BEA) has recently emerged as a min...
Analysis of the risk factors impact on the life quality of patients with arterial hypertension [0.03%]
高血压患者生活质量影响因素分析
Svitlana Pidruchna,Nadiya Yarema,Iryna Kuzmak et al.
Svitlana Pidruchna et al.
Objective. Recently, multicomponent quality-of-life indicators have become increasingly important in monitoring the health status of patients with hypertension and evaluating the effectiveness of treatment. Improving patient quality of life...
Correlation of triglyceride-glucose index, complement C5, and lipoprotein(a) with carotid intima-media thickness in thyroid dysfunction: A cross-sectional study [0.03%]
甲状腺功能异常患者TG、C5和Lp(a)与颈动脉内中膜厚度关系的横断面研究
Heri-Nugroho,Nurdopo Baskoro,Charles Limantoro et al.
Heri-Nugroho et al.
Objective. Thyroid dysfunction is associated with metabolic disturbances and an increased risk of atherosclerosis. This cross-sectional study investigated the relationships between the triglyceride-glucose index (TyG index), complement C5, ...
ERN1-dependent regulation of BAG cochaperone 1 expression and the sensitivity to glutamine deprivation in U87MG glioblastoma cells [0.03%]
ERN1依赖的BAG分子伴侣1表达调控及对U87MG胶质母细胞瘤细胞谷氨酰胺剥夺敏感性的影响
Yuliia M Viletska,Oleksandr H Minchenko,Olena O Khita et al.
Yuliia M Viletska et al.
Objective. The BAG cochaperone 1 (BAG1) binds to oncogene BCL2 and markedly enhances its anti-apoptotic effects. This cochaperone represents a link between growth factor receptors and anti-apoptotic mechanisms mediated by endoplasmic reticu...
Prevalence and predictors of poor glycemic control in patients with type 2 diabetes mellitus attending Alexandria Main University Hospital [0.03%]
亚历山大大学医院2型糖尿病患者不良血糖控制的流行病学及预测因素分析研究
Heba S Kassab,Fathy Z Alsewy,Sherif M Abdelaziz et al.
Heba S Kassab et al.
Objective. Despite the advances in diabetes management, there is still a high prevalence of poor glycemic control worldwide. This study aimed to determine the prevalence and predictors of poor glycemic control among patients with type 2 dia...
Circulating CXCL1 in newly diagnosed type 2 diabetes: context-dependent association with inflammatory load and metabolic indices [0.03%]
新诊断的2型糖尿病患者中的循环CXCL1：与炎症负荷和代谢指标的相关性取决于具体情况
Ali Zeynettin,Orhan Balikci,Ozden Yildirim Akan et al.
Ali Zeynettin et al.
Objective. Metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM) share a chronic low-grade inflammatory milieu driven by adiposity. C-X-C motif chemokine ligand 1 (CXCL1) has been linked to insulin resistance and endothelial dysfuncti...
Inhibition of ERN1 suppresses the expression of phosphoenolpyruvate carboxykinase 2 in U87MG glioblastoma cells and increases its sensitivity to glucose and glutamine deprivation [0.03%]
ERN1抑制作用可降低U87MG胶质母细胞瘤细胞中磷酸烯醇式丙酮酸羧基酶2的表达并增加其对葡萄糖和谷氨酰胺剥夺的敏感性
Yuliia M Viletska,Oleksandr H Minchenko,Olena O Khita et al.
Yuliia M Viletska et al.
Objective. Phosphoenolpyruvate carboxykinase (PCK) catalyzes the conversion of oxaloacetate to phosphoenolpyruvate and regulates pyruvate metabolism and gluconeogenesis in response to glucocorticoid and insulin stimuli. Mitochondrial isofor...
Effects of endocrine disruptor mixtures on functions of cultured porcine ovarian follicular cells [0.03%]
环境内分泌干扰物对体外培养猪卵巢卵泡细胞功能的影响
Alzbeta Bujnakova Mlynarcikova,Sona Scsukova
Alzbeta Bujnakova Mlynarcikova
Objective. Involvement of various endocrine disruptors (EDs) in pathophysiology of reproductive system disorders has been suggested previously. The studies have shown adverse effects of the individual substances, however, in the real-life s...
Hypokalemic metabolic alkalosis as a clinical clue to ectopic ACTH syndrome: two cases of neuroendocrine carcinoma [0.03%]
低钾性代谢性碱中毒作为异位ACTH综合征的临床线索：两例神经内分泌癌病例报告
Cundullah Torun,Erhan Eken,Bahar Cakır et al.
Cundullah Torun et al.
Objective. Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is a rare, but potentially life-threatening cause of Cushing's syndrome. Its clinical recognition may be delayed, especially when classical features of hypercortisolism ar...