Tributyltin chloride and triphenyltin chloride inhibit steroid hormone secretion by mouse Leydig cells TM3 and human adrenocortical cells H295R [0.03%]
三丁基锡和三苯基锡抑制小鼠支持细胞TM3及人肾上腺皮质H295R细胞类固醇激素的分泌
Dana Macejova,Alzbeta Berenikova,Julius Brtko et al.
Dana Macejova et al.
Objective. To find a possible balance between toxicity and potential anticancer activity of novel triorganotin compounds, retinoid X receptor (RXR) agonists, investigation the relationship between the structure, physicochemical properties, ...
Milder Form of Vici Syndrome Due to Novel Missense Variant in Epg5 Gene Affecting Splicing: A Case Report [0.03%]
Epg5基因错义突变影响剪接导致的Vici综合征轻型病例报告
Martina Skopkova,Katarina Brennerova,Maria Ostrozlikova et al.
Martina Skopkova et al.
Objective. Vici syndrome is a rare neurodevelopmental disorder with multisystem involvement, caused by mutations in the EPG5 gene encoding a protein involved in autophagy. It includes dysgenesis of the corpus callosum, cataracts, hypopigmen...
Beyond canonical GPCR: emerging roles of seven transmembrane proteins in metabolic control - insights from GPR180: A review [0.03%]
超越经典G蛋白偶联受体：GPR180在代谢调控中新兴作用的见解-综述文章
Lucia Balazova,Matus Antal,Miroslav Balaz
Lucia Balazova
G protein-coupled receptors (GPCRs) are traditionally defined by their seven-transmembrane (7TM) domain architecture and ability to activate heterotrimeric G proteins. However, accumulating evidence challenges this structure-centric view, r...
Tissue-specific steroid hormone-regulated secretion of proteins in Drosophila melanogaster salivary glands - molecular and genetic aspects: A review [0.03%]
果蝇唾腺组织特异性类固醇激素调节的蛋白质分泌-分子和遗传学观点综述
Robert Farkas,Denisa Benova-Liszekova,Milan Beno
Robert Farkas
Larval salivary glands (SGs) of Drosophila melanogaster (further Drosophila) are classical and well-known system, in which steroid hormone ecdysone controlling metamorphosis activates sequence of genes or transcriptional cascade that leads ...
Cardiac myocyte contractility, calcium dynamics, and morphology in Zucker diabetic fatty female and male rats - lacking data in this model of obesity and diabetes: A review [0.03%]
斑马 Zucker 糖尿病肥胖大鼠心肌细胞收缩力、钙动态和形态的改变——缺乏该肥胖及糖尿病模型中的数据：综述
Alexandra Zahradnikova,Hira Ijaz,Michal Cagalinec
Alexandra Zahradnikova
Diabetes mellitus (DM) represents an increasing global health burden with type 2 diabetes mellitus (T2DM) accounting for most cases. T2DM is associated with microvascular and macrovascular complications including myocardial ischemia and con...
Early life adversity influences brain development through neuroendocrine, immune, and microbiota-related mechanisms: A review [0.03%]
早期生活压力通过神经内分泌、免疫和肠道菌群相关机制影响大脑发育：综述文章
Peter Vargovic,Jana Osacka,Lubica Horvathova et al.
Peter Vargovic et al.
The early life experiences have an important impact on the development of the brain and behavior and early life adversities (ELA) may affect several biological systems including the hypothalamic-pituitary-adrenal (HPA) axis, neurotransmitte...
Endocannabinoid signalling in the regulation of hypothalamic-pituitary neuroendocrine circuits: A review [0.03%]
内源大麻素信号在下丘脑-垂体神经内分泌环路调控中的作用：综述
Anabela Nagyova,Natasa Hlavacova
Anabela Nagyova
The endocannabinoid system (ECS), comprising cannabinoid receptors, endogenous lipid ligands, and enzymes that regulate their synthesis and degradation, has emerged as an important modulator of neuroendocrine regulation. This review summari...
Current perspectives on the pathogenesis of multiple sclerosis: A minireview [0.03%]
当前对多发性硬化症发病机制的认识：一节微型综述
Zofia Radikova,Miroslav Tibensky,Lucia Mosna et al.
Zofia Radikova et al.
Multiple sclerosis (MS) is a chronic immune-mediated demyelinating disease of the central nervous system characterized by inflammation, reactive gliosis, and progressive neuroaxonal damage resulting in heterogeneous clinical and histopathol...
One genotype with a myriad of phenotypes: A family with multiple endocrine neoplasia [0.03%]
一个基因型与多种表现型：多发性内分泌肿瘤家系一例
Oumeyma Trimeche,Fatma Mnif,Fatma Abdelhedi et al.
Oumeyma Trimeche et al.
Objective. Multiple endocrine neoplasia type 1 (MEN1) is a very rare genetic disorder characterized by an autosomal dominant inheritance. We aim through this case series to delineate the wide spectrum of its clinical features. Methods. In t...
Modulation of appetite- and metabolism-regulating hormones after bariatric embolization, sleeve gastrectomy, and gastric plication [0.03%]
胃脏栓塞、袖状胃切除术和胃折叠术后调节食欲和代谢调节激素的作用
Andrii Prodan,Ihor Dzubanovsky,Yaroslav Ihorovych Havrysh
Andrii Prodan
Objective. The obesity is associated with profound disturbances in appetite-regulating and metabolic hormones including ghrelin, leptin, adiponectin, resistin, and insulin. Bariatric arterial embolization (BEA) has recently emerged as a min...