Effects of endocrine disruptor mixtures on functions of cultured porcine ovarian follicular cells [0.03%]
环境内分泌干扰物对体外培养猪卵巢卵泡细胞功能的影响
Alzbeta Bujnakova Mlynarcikova,Sona Scsukova
Alzbeta Bujnakova Mlynarcikova
Objective. Involvement of various endocrine disruptors (EDs) in pathophysiology of reproductive system disorders has been suggested previously. The studies have shown adverse effects of the individual substances, however, in the real-life s...
Hypokalemic metabolic alkalosis as a clinical clue to ectopic ACTH syndrome: two cases of neuroendocrine carcinoma [0.03%]
低钾性代谢性碱中毒作为异位ACTH综合征的临床线索：两例神经内分泌癌病例报告
Cundullah Torun,Erhan Eken,Bahar Cakır et al.
Cundullah Torun et al.
Objective. Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is a rare, but potentially life-threatening cause of Cushing's syndrome. Its clinical recognition may be delayed, especially when classical features of hypercortisolism ar...
LDL/HDL ratio and HOMA-IR as markers of severity of peripheral neuropathy in diabetic population [0.03%]
糖尿病患者中LDL/HDL比值和HOMA-IR作为外周神经病变严重程度的标志物
Anand Nisintha,Kumar Bhargavi,Thangavelu Saravanan
Anand Nisintha
Objective. Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus (T2DM) that substantially impairs quality of life. This study aimed to assess the relationship between metabolic parameters and DPN severit...
Observational Study
Endocrine regulations. 2025 Dec 12;59(1):217-226. DOI:10.2478/enr-2025-0025 2025
Association between shift work and levels of thyroid hormones and interleukin-37 [0.03%]
轮班工作与甲状腺激素水平及白细胞介素-37的相关性研究
Inaam Noori Ali,Noor Nihad Baqer,Hayder G Jawad
Inaam Noori Ali
Objective. Symptoms of thyroid defects involve sleep disorders, gain or loss of weight, tremors of hand, constipation, dry skin, bradycardia, diarrhea, irregular menses, and hot or cold tolerance. Workers in different professions face diffe...
Mitochondria-targeting compounds for management of metabolic and hemostatic abnormalities associated with heart dysfunctions in experimental type 2 diabetes [0.03%]
靶向线粒体化合物可治疗实验型2型糖尿病心脏功能异常相关的代谢和凝血障碍
Tamara Kuchmerovska,Lesya Yanitska,Oksana Horkunenko et al.
Tamara Kuchmerovska et al.
Objective. Cardiovascular complications are highly prevalent in type 2 diabetes mellitus (T2DM) driven by obesity, dyslipidemia, hypertension, and hypercoagulability associated with insulin resistance. The purpose of this study was to eluci...
Mirtazapine for gastrointestinal side effects of glucagon-like peptide-1 receptor agonist therapy in older adults [0.03%]
米塔扎平治疗老年患者GLP-1受体激动剂治疗的胃肠道不良反应
Ali R Khan,Gennifer Wahbah Makhoul,Mukaila A Raji
Ali R Khan
Objective. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) play a role in management of type 2 diabetes (T2D) and obesity by promoting glycemic control and weight reduction. Beyond these benefits, GLP-1 RAs have demonstrated positive ...
Endogenous intoxication and morpho-functional changes in the liver during experimental acute generalized peritonitis in diabetic rats [0.03%]
糖尿病 rats 急性弥漫性腹膜炎内毒血症的变化及肝morpho-功能改变
Bohdana Verveha,Mariana Kondro,Petro Bodnar
Bohdana Verveha
Objective. The study aims to evaluate the severity of endogenous intoxication and characterize morpho-functional liver changes during experimental acute generalized peritonitis (AGP) in diabetic rats. Methods. Fifty-six adult male Wistar ra...
Post-radiation hypothyroidism in patients with head and neck tumors: An overview assessment [0.03%]
头颈部肿瘤患者放射治疗后甲状腺功能减退症的综合评估
Elena Bukvayova,Maria Kafkova
Elena Bukvayova
Head and neck tumors are common in Slovakia. Although the number of tumors associated with smoking and alcohol is decreasing, the number of tumors associated with human papilloma-virus increases. Radiotherapy plays an important role in thei...
Propylthiouracil-induced agranulocytosis complicated by severe infection in a patient with Graves' disease: A case report [0.03%]
格雷夫斯病患者发生他巴唑所致的中性粒细胞缺乏并发严重感染一例报告
Jens Skjoldan Svenningsen,Djordje Marina
Jens Skjoldan Svenningsen
Objective. Graves' disease is an autoimmune disease of the thyroid gland causing hyperthyroidism due to thyroid-stimulating hormone receptor autoantibodies. A rare, but serious complication of anti-thyroid drug therapy is agranulocytosis, a...
Hypoxic regulation of insulin receptor substrate 2 gene expression is differently regulated by endoplasmic reticulum stress and hydrocortisone in normal human astrocytes and glioblastoma cells [0.03%]
内质网应激和氢化可的松在正常人类星形胶质细胞和胶质母细胞瘤细胞中对缺氧调节胰岛素受体底物2基因表达的不同调控作用
Oleksandr H Minchenko,Yuliia M Viletska,Anastasiia I Abramchuk et al.
Oleksandr H Minchenko et al.
Objective. The insulin receptor substrate 2 (IRS2) is phosphorylated by the tyrosine kinase activity of the insulin receptor and the insulin-like growth factor I (IGF-1) receptor upon receptor stimulation. It mediates insulin signaling cont...