Mitochondria-targeting compounds for management of metabolic and hemostatic abnormalities associated with heart dysfunctions in experimental type 2 diabetes [0.03%]
靶向线粒体化合物可治疗实验型2型糖尿病心脏功能异常相关的代谢和凝血障碍
Tamara Kuchmerovska,Lesya Yanitska,Oksana Horkunenko et al.
Tamara Kuchmerovska et al.
Objective. Cardiovascular complications are highly prevalent in type 2 diabetes mellitus (T2DM) driven by obesity, dyslipidemia, hypertension, and hypercoagulability associated with insulin resistance. The purpose of this study was to eluci...
Mirtazapine for gastrointestinal side effects of glucagon-like peptide-1 receptor agonist therapy in older adults [0.03%]
米塔扎平治疗老年患者GLP-1受体激动剂治疗的胃肠道不良反应
Ali R Khan,Gennifer Wahbah Makhoul,Mukaila A Raji
Ali R Khan
Objective. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) play a role in management of type 2 diabetes (T2D) and obesity by promoting glycemic control and weight reduction. Beyond these benefits, GLP-1 RAs have demonstrated positive ...
Endogenous intoxication and morpho-functional changes in the liver during experimental acute generalized peritonitis in diabetic rats [0.03%]
糖尿病 rats 急性弥漫性腹膜炎内毒血症的变化及肝morpho-功能改变
Bohdana Verveha,Mariana Kondro,Petro Bodnar
Bohdana Verveha
Objective. The study aims to evaluate the severity of endogenous intoxication and characterize morpho-functional liver changes during experimental acute generalized peritonitis (AGP) in diabetic rats. Methods. Fifty-six adult male Wistar ra...
Post-radiation hypothyroidism in patients with head and neck tumors: An overview assessment [0.03%]
头颈部肿瘤患者放射治疗后甲状腺功能减退症的综合评估
Elena Bukvayova,Maria Kafkova
Elena Bukvayova
Head and neck tumors are common in Slovakia. Although the number of tumors associated with smoking and alcohol is decreasing, the number of tumors associated with human papilloma-virus increases. Radiotherapy plays an important role in thei...
Propylthiouracil-induced agranulocytosis complicated by severe infection in a patient with Graves' disease: A case report [0.03%]
格雷夫斯病患者发生他巴唑所致的中性粒细胞缺乏并发严重感染一例报告
Jens Skjoldan Svenningsen,Djordje Marina
Jens Skjoldan Svenningsen
Objective. Graves' disease is an autoimmune disease of the thyroid gland causing hyperthyroidism due to thyroid-stimulating hormone receptor autoantibodies. A rare, but serious complication of anti-thyroid drug therapy is agranulocytosis, a...
Hypoxic regulation of insulin receptor substrate 2 gene expression is differently regulated by endoplasmic reticulum stress and hydrocortisone in normal human astrocytes and glioblastoma cells [0.03%]
内质网应激和氢化可的松在正常人类星形胶质细胞和胶质母细胞瘤细胞中对缺氧调节胰岛素受体底物2基因表达的不同调控作用
Oleksandr H Minchenko,Yuliia M Viletska,Anastasiia I Abramchuk et al.
Oleksandr H Minchenko et al.
Objective. The insulin receptor substrate 2 (IRS2) is phosphorylated by the tyrosine kinase activity of the insulin receptor and the insulin-like growth factor I (IGF-1) receptor upon receptor stimulation. It mediates insulin signaling cont...
Effect of aripiprazole and improved living conditions on behavioral manifestations and neurogenic markers expression in an animal model of PTSD [0.03%]
阿立哌唑和改善生活条件对PTSD动物模型行为表现及神经源性标志物表达的影响
Jana Osacka,Lubica Horvathova,Lila Dziewiczova et al.
Jana Osacka et al.
Objective. Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder that can develop after exposure to a severe traumatic event and is connected with behavioral changes and adult neurogenesis impairment. Atypical antipsychoti...
Oral health-related behaviors and prevalence of thyroid diseases in Iranian patients [0.03%]
伊朗患者的口腔健康相关行为与甲状腺疾病的患病率
Fatemeh Fadakar Davarani,Mojgan Sanjari,Amir Hossein Nekouei et al.
Fatemeh Fadakar Davarani et al.
Objective. Thyroid disorders can affect the general health-related quality of life with complications such as fatigue, anxiety, depression, and systemic manifestations. The aim of this study was to investigate the relationship between the o...
Ali Karadeniz
Ali Karadeniz
Diabetes mellitus has become a major global health concern with increasing prevalence worldwide. Recent studies have highlighted the critical role of the circadian rhythm, the body's internal biological clock, in the pathogenesis of diabete...
Impact of GHRL (RS696217) and LEPR (RS1137101) gene polymorphisms on hormonal and anthropometric outcomes after bariatric surgery [0.03%]
胃抑制多肽和脂联素基因多态性对代谢手术效果影响的纵向研究
Andrii Prodan
Andrii Prodan
Objective. The aim of the study was to evaluate the influence of GHRL (rs696217) and LEPR (rs1137101) gene polymorphisms on weight loss dynamics and endocrine marker changes following various bariatric procedures. Patients and Methods. A to...