Alexander Bracke,Grazyna Domanska,Katharina Bracke et al.
Alexander Bracke et al.
Currently, it is controversially discussed whether a relationship between obesity and cognition exists. We here analyzed a mouse model of obesity (leptin-deficient mice) to study the effects of obesity on the morphology of the hippocampus (...
Neurological Disease Modelling for Spinocerebellar Ataxia Using Zebrafish [0.03%]
使用斑马鱼模拟脊小脑共济失调的神经退行性疾病模型
Kazuhiko Namikawa,Alessandro Dorigo,Reinhard W Köster
Kazuhiko Namikawa
The cerebellum integrates sensory information and motor actions. Increasing experimental evidence has revealed that these functions as well as the cerebellar cytoarchitecture are highly conserved in zebrafish compared with mammals. However,...
A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis [0.03%]
TDP-43和DNA损伤反应在肌萎缩侧索硬化症中的作用的评论文章
Joy Mitra,Muralidhar L Hegde
Joy Mitra
Amyotrophic lateral sclerosis (ALS) is a devastating, motor neuron degenerative disease without any cure. About 95% of the ALS patients feature abnormalities in the RNA/DNA-binding protein, TDP-43, involving its nucleo-cytoplasmic mislocali...
Future Directions in Examining Neurological Adaptation to Bilingual Experiences [0.03%]
探究双语经验神经适应性的未来方向
Vincent DeLuca
Vincent DeLuca
In recent years, research examining the neurocognitive effects of bilingualism has undergone a shift in focus towards examining the neurocognitive effects of individual differences within specific aspects of language experience. The DeLuca ...
Blast-Related Traumatic Brain Injury: Current Concepts and Research Considerations [0.03%]
爆炸引起的创伤性脑损伤：当前概念与研究考量
Daniel W Bryden,Jessica I Tilghman,Sidney R Hinds nd
Daniel W Bryden
Traumatic brain injury (TBI) is a well-known consequence of participation in activities such as military combat or collision sports. But the wide variability in eliciting circumstances and injury severities makes the study of TBI as a unifo...
ZPR1-Dependent Neurodegeneration Is Mediated by the JNK Signaling Pathway [0.03%]
JNK信号通路介导的依赖于ZPR1的神经退行性病变
Xiaoting Jiang,Annapoorna Kannan,Laxman Gangwani
Xiaoting Jiang
The zinc finger protein ZPR1 deficiency causes neurodegeneration and results in a mild spinal muscular atrophy (SMA)-like disease in mice with reduced Zpr1 gene dosage. Mutation of the survival motor neuron 1 (SMN1) gene causes SMA. Spinal ...
Quantification of surviving neurons after contusion, dislocation, and distraction spinal cord injuries using automated methods [0.03%]
利用自动化方法定量评估不同损伤类型的脊髓损伤后存活的神经元数量
Jingchao Wang,Meiyan Zhang,Yue Guo et al.
Jingchao Wang et al.
This study proposes and validates an automated method for counting neurons in spinal cord injury (SCI) and then uses it to examine and compare the surviving cells in common types of SCI mechanisms. Moderate contusion, dislocation, and distr...
Walking Function After Cervical Contusion and Distraction Spinal Cord Injuries in Rats [0.03%]
颈椎震荡和脊髓牵拉伤后大鼠的步行功能恢复
Yue Guo,Hai Hu,Jingchao Wang et al.
Yue Guo et al.
This study examines and compares the walking function in contusion and distraction spinal cord injury (SCI) mechanisms. Moderate contusion and distraction SCIs were surgically induced between C5 and C6 in Sprague-Dawley male rats. The CatWa...
A Further Analysis and Commentary on: Profiling Changes in Cortical Astroglial Cells Following Chronic Stress [0.03%]
慢性应激后纹状体 astroglia 细胞变化的进一步分析与评述
Gianfilippo Coppola,Gareth M Rurak,Stephanie Simard et al.
Gianfilippo Coppola et al.
The neuroplasticity hypothesis of depression proposes that major depressive disorders are related to decreased hippocampal and cortical neural plasticity, which is reversed by antidepressant treatment. Astroglial cells have emerged as key m...
Why Is Mom Stressed: Homeorhesis as the Potential Problem and Nicotinamide Riboside as the Potential Solution [0.03%]
为什么妈妈压力山大？体内平衡紊乱导致的慢性压力及烟酰胺核糖的潜在解决方案
Charles Brenner
Charles Brenner
The remodeling of female mammalian physiology to support the development of a fertilized egg into an externally breathing individual and then to provide all the nutrition to this individual while remodeling back to nearly her pregestational...