A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis
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Amyotrophic lateral sclerosis (ALS) is a devastating, motor neuron degenerative disease without any cure. About 95% of the ALS patients feature abnormalities in the RNA/DNA-binding protein, TDP-43, involving its nucleo-cytoplasmic mislocalization in spinal mot... ...
