Diagnosis and Management of Gastroesophageal Reflux Disease: Current Insights [0.03%]
胃食管反流病的诊断和管理：当前见解
Abhinav Vayal-Veettil,C Prakash Gyawali
Abhinav Vayal-Veettil
Gastroesophageal reflux disease (GERD) results from retrograde movement of gastric content into the esophagus and beyond, resulting in symptoms, mucosal injury and long-term complications. Typical symptoms of heartburn and regurgitation are...
Primary Biliary Cholangitis and Seropositive Rheumatoid Arthritis: A Two-Sample Mendelian Randomization Study [0.03%]
原发性胆汁性胆管炎与类风湿关节炎的遗传关联：两样本孟德尔随机化研究
Zongqi Deng,Wanyang Lei,Xiao Kuang et al.
Zongqi Deng et al.
Background: Observational studies indicated potential associations between primary biliary cholangitis (PBC) and rheumatoid arthritis (RA). However, the causal relationship between RA and PBC remains unclear and controver...
Microbial Patterns in Newly Diagnosed Inflammatory Bowel Disease Revealed by Presence and Transcriptional Activity - Relationship to Diagnosis and Outcome [0.03%]
肠道新诊断的炎症性肠病中的微生物模式及其与诊断和预后的关联
Simen Svendsen Vatn,Simen Hyll Hansen,Tone Møller Tannæs et al.
Simen Svendsen Vatn et al.
Background: As part of the IBD Character initiative, we examined an inception cohort and investigated mucosal microbiota composition and transcriptional activity in relation to clinical outcomes. ...
Is Primary Opening of Fistula-in-Ano Always at Dentate Line: Correlation Between MRI and Operative Findings in 379 Patients [0.03%]
肛瘘原发开口均位于齿线处吗？379例患者术前磁共振成像与术后解剖学表现分析
Pankaj Garg,Gabriele Naldini,Vincent De Parades et al.
Pankaj Garg et al.
Background: The primary opening of the cryptoglandular fistula-in-ano is generally assumed to be present at the dentate line as the cryptoglandular glands open there. However, no study has ever systematically studied the ...
Expert Opinion on the Management, Challenges, and Knowledge Gaps Pertaining to Eosinophilic Esophagitis Among Adults in the Greater Gulf Region [0.03%]
关于加勒比地区成人嗜酸性食管炎管理、挑战和知识空白的专家意见
Ahmad Jazzar,Ahmed Al-Darmaki,Evan Samuel Dellon et al.
Ahmad Jazzar et al.
Eosinophilic esophagitis (EoE) is a type 2 inflammatory esophageal disease that presents in adults as dysphagia and food impaction. EoE is characterized by a predominance of T helper 2 cells among the T cell population. Environmental agents...
Biliary Microbial Community and Metabolic Potential in Patients with Multiple Common Bile Duct Stones [0.03%]
多发胆总管结石患者胆汁微生物群及其代谢潜能
Tingting Xia,Shuo Feng,Zigui Zou et al.
Tingting Xia et al.
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is widely used in the treatment of choledocholithiasis, while successful extraction of common bile duct stone (CBDS) is commonly hampered by the number of ...
Isolation of Murine Pancreatic Stellate Cells and the Establishment of a New ex-vivo Activation Model [0.03%]
小鼠胰星状细胞的分离及其体外活化模型的建立
Xinye Wang,Miaomiao Li,Xinjuan Liu et al.
Xinye Wang et al.
Background: Pancreatic stellate cells (PSCs) are critical in the development of pancreatic fibrosis. In vitro, cell attachment itself can promote cell activation. Currently, there is a lack of methods for isolating activa...
Regional Trends in Inflammatory Bowel Disease-Related Mortality in the US from 1999 to 2022 [0.03%]
1999年至2022年美国炎症性肠病相关死亡率的地区变化趋势
Saif Zurob,Alexandra Brown,Taylor Billion et al.
Saif Zurob et al.
Purpose: Inflammatory bowel disease (IBD) is a grouping of chronic inflammatory diseases of the gastrointestinal tract that affects upwards of 2.4 million Americans. Despite its prevalence, the exact cause remains unknown...
A CDKN2B-Associated Immune Prognostic Model for Predicting Immune Cell Infiltration and Prognosis in Esophageal Carcinoma [0.03%]
基于CDKN2B相关免疫标志物的食管癌预后模型及免疫细胞浸润评估能力研究
Xiulan Peng,Juping Han,Juan Huang et al.
Xiulan Peng et al.
Objective: Studies have indicated that cyclin dependent protein kinase inhibitor 2B (CDKN2B) deletion is one of the most common changes in esophageal cancer (EC) which affects its progression and prognosis. This study exp...
Elevated Expression of CHAF1A in Hepatocellular Carcinoma Progression and Immune Modulation [0.03%]
肝细胞癌进展和免疫调节中CHAF1A的高表达
Jiajing Li,Ting Zhang,Qi Liu et al.
Jiajing Li et al.
Purpose: This study aimed to explore the role of CHAF1A in hepatocellular carcinoma (HCC) progression, focusing on its expression, co-expression genes, genomic alterations, promoter methylation, clinical relevance, progno...