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Gastric Proton Pumpopathy Associated with Protein Sorting Machinery: A Narrative Review

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Background: Gastric acid secretion by parietal cells depends on the trafficking and exocytosis of H⁺/K⁺-ATPase-rich tubulovesicles (TVs) to the apical membrane in response to histamine stimulation via cyclic AMP elevation. Howe... ...