Secondary acute myeloid leukemia and early infection are independent predictors of poor survival in acute myeloid leukemia treated with hypomethylating agents and venetoclax [0.03%]
二代急性髓系白血病和早期感染是低甲基化剂和维奈克拉治疗急性髓系白血病预后不良的独立预测因素
Stefano Cordella,Davide Giusti,Eleonora De Bellis et al.
Stefano Cordella et al.
Treatment-free remission as a new goal in the management of chronic myeloid leukemia: Clinical and biological aspects [0.03%]
治疗免费缓解作为慢性髓系白血病管理的新目标：临床和生物学方面
Daniele Cattaneo,Cristina Bucelli,Valentina Bellani et al.
Daniele Cattaneo et al.
The therapeutic armamentarium of chronic myeloid leukemia (CML) has dramatically improved after small molecule tyrosine kinase inhibitors (TKIs) targeting BCR::ABL1 became available, with a life expectancy now close to that of the general p...
Bruton tyrosine kinase inhibitor monotherapy in B-cell lymphoma and risk of infection: A systematic review and meta-analysis of randomized controlled trials [0.03%]
布鲁顿酪氨酸激酶抑制剂单药治疗B细胞淋巴瘤感染风险的系统评价和Meta分析
Mohammed Zuber,Samruddhi Nandkumar Borate,Pooja Gokhale et al.
Mohammed Zuber et al.
Bruton's tyrosine kinase (BTK) inhibitors are important therapeutic advances with promising efficacy outcomes in the treatment of patients with chronic lymphocytic leukemia and other B-cell lymphoma subtypes. However, the utility of BTK inh...
Research on the mechanism of HOPX-HDAC2 interaction inducing differentiation blockage in acute myeloid leukemia [0.03%]
HOPX-HDAC2相互作用诱导急性髓系白血病分化阻滞的机制研究
Fang He,Yan Tu,Lihong Ni
Fang He
Homeodomain-only protein homeobox (HOPX) mainly exerts its transcriptional repression by physically sequestering the serum co-repressor and recruiting histone deacetylase (HDAC), possessing important potential as a prognostic gene in acute ...
Combined targeting of Hedgehog/GLI1 and Wnt/β-catenin pathways in mantle cell lymphoma [0.03%]
套细胞淋巴瘤中外源性靶向 Hedgehog/GLI1 和 Wnt/β-catenin 信号途径的联合抑制作用
Yan Han,Chuntuan Li,Shengquan Liu et al.
Yan Han et al.
Mantle cell lymphoma (MCL) is a rare and aggressive form of non-Hodgkin lymphoma. Challenges in its treatment include relapse, drug resistance, and a short survival period. The Hedgehog/GLI1 (Hh/GLI1) and Wnt/β-catenin pathways are crucial...
Characteristics, outcomes and health care utilization of patients with acute myeloid leukemia aged 70 years or older: A single-center retrospective analysis [0.03%]
老年急性髓系白血病患者的临床特点、结局及卫生服务利用特征：一项单中心回顾分析
Marie Anne-Catherine Neumann,Jan-Hendrik Naendrup,Jorge Garcia Borrega et al.
Marie Anne-Catherine Neumann et al.
The overall prognosis of older patients with acute myeloid leukemia (AML) is dismal. Only a small subgroup experiences long-term survival. The discrimination between patients who are candidates for potentially curative approaches and those ...
Efficacy of escalating therapy with brentuximab vedotin-AVD in advanced stage Hodgkin lymphoma patients with positive interim positron emission tomography after ABVD [0.03%]
布雷卡德联合AVD治疗ABVD方案二线治疗后阳性 interim PET的晚期霍奇金淋巴瘤患者的疗效分析
Carmen Martínez,Esther Carcelero,Antonio Gutiérrez et al.
Carmen Martínez et al.
Patients with advanced-stage Hodgkin lymphoma treated with ABVD who have a positive interim FDG-PET (iPET) have a poor prognosis. Escalation to BEACOPP has been shown to improve progression-free survival (PFS). However, randomized trials ar...
Adverse impact of 1q amplification on outcomes in patients with multiple myeloma treated with daratumumab, carfilzomib and dexamethasone in a real-world clinical setting [0.03%]
达雷木单抗、卡非佐米和地塞米松治疗多发性骨髓瘤患者时1q扩增对其预后的影响：真实世界临床研究数据的分析
Taku Kikuchi,Nobuhiro Tsukada,Kodai Kunisada et al.
Taku Kikuchi et al.
From trials to statistical insights: Bortezomib's story in childhood T-cell lymphoid malignancies [0.03%]
硼替佐米治疗儿童T细胞淋巴瘤的探索之路
Shyam Srinivasan
Shyam Srinivasan
Clinical characteristics and outcome of early-stage diffuse large B cell lymphoma of female genital track: A retrospective study of the Hellenic cooperative lymphoma group [0.03%]
女性生殖道来源早期弥漫大B细胞淋巴瘤的临床特征及预后分析：希腊淋巴瘤协作组的一项回顾性研究
Evgenia Verrou,Sotirios G Papageorgiou,Maria Bouzani et al.
Evgenia Verrou et al.
Involvement of female genital track (FGT) by diffuse large B cell lymphoma (DLBCL) represents an extremely rare diagnosis. Especially data regarding early-stage disease (i.e., IE, IIE) is very limited. Importantly, previous studies showed c...