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Research on the mechanism of HOPX-HDAC2 interaction inducing differentiation blockage in acute myeloid leukemia

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Homeodomain-only protein homeobox (HOPX) mainly exerts its transcriptional repression by physically sequestering the serum co-repressor and recruiting histone deacetylase (HDAC), possessing important potential as a prognostic gene in acute myeloid leukemia (AM... ...