Managing Treatment-Emergent Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome Following CAR-T Cell Therapy: A Case-Based Review of the use of Emapalumab [0.03%]
基于emapalumab使用经验的CAR-T细胞治疗继发效应性免疫细胞活化型噬血细胞性淋巴组织细胞增生症综合征的管理：病例综述
Livia Donzelli,Veronica Zullino,Giovanni Fernando Torelli et al.
Livia Donzelli et al.
Chimeric antigen receptor T (CAR-T) cell therapies have revolutionized the treatment of hematological malignancies, achieving high response rates in patients with relapsed or refractory disease. Despite these benefits, CAR-T cell therapies ...
Treatment Cessation in Chronic Myeloid Leukemia: Evidence and Uncertainties [0.03%]
慢性粒细胞白血病的治疗停药：证据与不确定性
Jiří Mayer
Jiří Mayer
Testing to discontinue imatinib already started some years after the advent of this new CML therapy. Since that time, despite many trials and studies in this field, there are still significant gaps, and many fundamental questions remain una...
Outcome of Adult Lymphoblastic Lymphoma Patients Treated in the Real Life According to the Gimema LAL1913 Protocol: A Campus ALL Multicenter Study [0.03%]
意大利GIMEMA淋巴瘤研究小组根据成人急性淋巴细胞白血病研究协作组LAL1913方案治疗成人淋巴母细胞淋巴瘤患者的疗效：一项校区ALL多中心研究
M Delia,D Lazzarotto,S Imbergamo et al.
M Delia et al.
The introduction of pediatric-inspired chemotherapy protocols for acute lymphoblastic leukemia (ALL) in the setting of adult patients affected by lymphoblastic lymphoma (LL) has improved the results in terms of outcomes. Within the Campus A...
Multicenter Study
Hematological oncology. 2025 Nov;43(6):e70153. DOI:10.1002/hon.70153 2025
Fatigue, Neuropathy and Psychological Distress and Their Association With Health-Related Quality of Life in Survivors of Diffuse Large B-Cell Lymphoma: A Prospective Cohort Study and Comparison With a Normative Population [0.03%]
弥漫性大B细胞淋巴瘤幸存者的疲劳，神经病变和心理困扰及其与健康相关生命质量的关联：前瞻性队列研究及与标化人群对比研究
Suzanne I M Neppelenbroek,Afke Ekels,Marie José Kersten et al.
Suzanne I M Neppelenbroek et al.
We investigated the course of fatigue, neuropathy, psychological distress and their impact on HRQoL among diffuse large B-Cell Lymphoma (DLBCL) survivors up to 13 years after diagnosis, and compared it to an age- and sex-matched population....
Comparative Study
Hematological oncology. 2025 Nov;43(6):e70151. DOI:10.1002/hon.70151 2025
Real-World Data Analysis on Early Mortality in Chinese Multiple Myeloma Patients: Analysis of 1093 Patients During a 15-Year Period [0.03%]
中国多发性骨髓瘤患者早期死亡的真实世界数据分析：一项长达15年的1093例分析研究
Xue Yang,Pu Wang,Tianhong Xu et al.
Xue Yang et al.
Despite the survival benefit observed in recent decades, early mortality (EM) remains critical in newly diagnosed multiple myeloma (NDMM) patients, with heterogeneous definitions and risk factors across studies. Besides, prognostic models f...
Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With Lymphoma [0.03%]
淋巴瘤患者一线化疗后肌肉质量、肌力和体能变化的回顾性研究
Charlotte Nørregaard Grønset,Mary Jarden,Jan Christensen et al.
Charlotte Nørregaard Grønset et al.
Lymphomas are common cancers affecting the lymphatic system. Chemotherapy is a standard treatment, yet its impact on patient's physical capacity remains understudied. This study aimed to evaluate changes in body composition, muscle strength...
Defining and Addressing the Current Unmet Medical Needs for the Frontline Treatment of Advanced Stage Aggressive Large B-Cell Lymphoma: A Perspective From an Ad Hoc Panel of Italian Experts [0.03%]
意大利专家特设工作组关于侵袭性大B细胞淋巴瘤前线治疗未满足的医学需求的见解及应对策略
Antonio Pinto,Carmelo Carlo-Stella,Monia Marchetti et al.
Antonio Pinto et al.
Aggressive large B-cell lymphomas (LBCL) include a range of disease types characterized by heterogenous histopathologic, molecular, and genetic features. In this review, we summarize the main standardized disease assessments, treatments and...
Identification of Copy Number Alterations From Shallow Whole-Genome Sequencing in Multiple Myeloma [0.03%]
基于浅层全基因组测序的多发性骨髓瘤拷贝数变异识别
Jiali Li,Shaobing Gao,Zhenling Li et al.
Jiali Li et al.
Multiple myeloma (MM) is a malignant neoplasm of plasma cells leading to bone destruction and marrow failure. Prognosis and management of MM rely on cytogenetic determination of copy number alterations (CNAs). Nevertheless, karyotype analys...
Indolent T-Cell Lymphoma of the Gastrointestinal Tract Associated With Strongyloides Stercoralis Infection [0.03%]
肠道丝虫感染伴发的惰性T细胞淋巴瘤
Yue Zhao,Philip Petersen,Imran Siddiqi et al.
Yue Zhao et al.
Clinical and Prognostic Impact of Allelic Status in EZH2-Mutated Myeloid Neoplasms [0.03%]
EZH2突变髓系肿瘤的等位基因状态的临床和预后影响
Muhamad Oum,Ahmad Nanaa,Yazan Jabban et al.
Muhamad Oum et al.