Retraction for Piracha et al., "Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3β/β-Catenin Signaling Pathway" [0.03%]
撤回：Piracha等，“沉默信息调节因子2异构体1通过AKT/GSK-3β/β-Catenin信号通路增强乙型肝炎病毒RNA转录和DNA合成”
Zahra Zahid Piracha,Hyeonjoong Kwon,Umar Saeed et al.
Zahra Zahid Piracha et al.
Ebola virus' hidden target: virus transmission to and infection of skin [0.03%]
埃博拉病毒的隐秘攻击目标：病毒感染和传播至皮肤及其作用机制
Paige T Richards,Anthony M Fleck,Radhika Patel et al.
Paige T Richards et al.
Ebola virus (EBOV), the causative agent of Ebola virus disease, remains one of the World Health Organization's top 10 threats to global health. Infectious EBOV virions can be found on the surface of skin late in infection and may be transmi...
Broad-spectrum vaccines against various and evolving viruses: from antigen design to nanoparticle delivery [0.03%]
广谱抗病毒疫苗：从抗原设计到纳米颗粒递送
Mengxiang Cao,Yongfeng Li,Xin Song et al.
Mengxiang Cao et al.
Pathogen evolution and narrow vaccine coverage urgently demand broad-spectrum vaccines. This review explores two pivotal technological fronts: structural biology- and immunoinformatics-guided antigen design, and utilizing nanoparticle-based...
Solution structure of the C-terminal domain of the measles virus V protein in its free form and mechanistic analysis of STAT2 targeting [0.03%]
游离形式的麻疹病毒V蛋白C端结构及其针对STAT2的作用机理分析
Kaho Morita,Nanaka Goda,Madoka Kimoto et al.
Kaho Morita et al.
Viruses commonly evade the host antiviral interferon (IFN) response by targeting key components of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, typically STAT1 and STAT2. Among the well-characterized...
A recombinant Marek's disease vaccine candidate provides complete protection against infectious bursal disease virus and H9 subtype avian influenza virus in chickens [0.03%]
一种重组马立克氏病疫苗候选疫苗可为鸡提供完全的传染性法氏囊病病毒和禽流感H9亚型病毒感染保护
Wenrui Fan,Xianying Zeng,Yuntong Chen et al.
Wenrui Fan et al.
Vaccination is the most effective preventative measure against economically devastating poultry diseases, such as infectious bursal disease (IBD), H9 subtype avian influenza (AI), and Marek's disease. In recent decades, various vaccination ...
From phenotype to receptor: validating physiological clustering of Escherichia coli phages through comprehensive receptor analysis [0.03%]
从表型到受体：通过全面的受体分析验证大肠杆菌噬菌体的生理聚类
Tomoyoshi Kaneko,Toshifumi Osaka,Minoru Inagaki et al.
Tomoyoshi Kaneko et al.
Understanding the relationship between bacteriophage (phage) classification and target receptors is crucial for phage ecology and applied research. In this study, we compared 13 previously isolated Escherichia coli phages based on physiolog...
Replication-competent adenovirus reporters utilizing endogenous viral expression architecture [0.03%]
利用内源性病毒表达结构的具有复制能力的腺病毒报告系统
Claire M O&#x;Brien,Lorenzo Serra,Molly R Patterson et al.
Claire M O&#x;Brien et al.
Adenoviruses are double-stranded DNA viruses widely used as platforms for vaccines, oncolytics, and gene delivery. However, tools for studying adenoviral gene expression in real time during infection remain limited. Here, we describe a set ...
Oropouche virus NSs protein suppresses host transcription by targeting the RNA polymerase II RPB1 protein [0.03%]
雅可他病毒NSs蛋白通过作用于RNA聚合酶II的RPB1亚基抑制宿主基因转录
Eduardo Jurado-Cobena,Cigdem Alkan,Tetsuro Ikegami
Eduardo Jurado-Cobena
Oropouche fever is a debilitating disease caused by Oropouche virus (OROV), an arthropod-borne member of the Peribunyaviridae family. Despite its public health significance, the molecular mechanisms driving OROV pathogenesis remain poorly u...
The mammalian SKI complex is a broad-spectrum antiviral drug target that upregulates cellular cholesterol to inhibit viral replication [0.03%]
哺乳动物SKI复合物是一种广谱的抗病毒药物靶点，可上调细胞胆固醇以抑制病毒感染复制
Stuart Weston,Lauren Baracco,Louis Taylor et al.
Stuart Weston et al.
There is a need for the development of broad-spectrum antiviral compounds that can act as first-line therapeutic countermeasures to emerging viral infections. Host-directed approaches present a promising avenue of development and carry the ...
The leader proteins of Theiler's virus and Boone cardiovirus use a combination of short linear motifs (SLiMs) to target RSK kinases to the nuclear pore complex [0.03%]
Theiler病毒和Boone心血管病毒的领导蛋白使用一系列短线性基序(SLiMs)将RSK激酶靶向至核孔复合体
Belén Lizcano-Perret,Fanny Wavreil,Martin Veinstein et al.
Belén Lizcano-Perret et al.
Unrelated pathogens, including viruses and bacteria, use a common short linear motif (SLiM) to interact with cellular kinases of the RSK (p90 S6 ribosomal kinase) family. Such a "DDVF" (D/E-D/E-V-F) SLiM occurs in the leader (L) protein enc...