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Solution structure of the C-terminal domain of the measles virus V protein in its free form and mechanistic analysis of STAT2 targeting

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Viruses commonly evade the host antiviral interferon (IFN) response by targeting key components of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, typically STAT1 and STAT2. Among the well-characterized viral IFN antagonis... ...