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期刊名:Cell

缩写:CELL

ISSN:0092-8674

e-ISSN:1097-4172

IF/分区:42.5/Q1

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共收录本刊相关文章索引9608
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Philipp Schwartenbeck,Alon Baram,Yunzhe Liu et al. Philipp Schwartenbeck et al.
Human reasoning depends on reusing pieces of information by putting them together in new ways. However, very little is known about how compositional computation is implemented in the brain. Here, we ask participants to solve a series of pro...
Ofer Zimmerman,Maxwell I Zimmerman,Saravanan Raju et al. Ofer Zimmerman et al.
MXRA8 is a receptor for chikungunya (CHIKV) and other arthritogenic alphaviruses with mammalian hosts. However, mammalian MXRA8 does not bind to alphaviruses that infect humans and have avian reservoirs. Here, we show that avian, but not ma...
Dirk Mossmann,Christoph Müller,Sujin Park et al. Dirk Mossmann et al.
Metabolic reprogramming is a hallmark of cancer. However, mechanisms underlying metabolic reprogramming and how altered metabolism in turn enhances tumorigenicity are poorly understood. Here, we report that arginine levels are elevated in m...
Connor A Tsuchida,Nadav Brandes,Raymund Bueno et al. Connor A Tsuchida et al.
CRISPR-Cas9 genome editing has enabled advanced T cell therapies, but occasional loss of the targeted chromosome remains a safety concern. To investigate whether Cas9-induced chromosome loss is a universal phenomenon and evaluate its clinic...
Nora Schmidt,Sabina Ganskih,Yuanjie Wei et al. Nora Schmidt et al.
Regulation of viral RNA biogenesis is fundamental to productive SARS-CoV-2 infection. To characterize host RNA-binding proteins (RBPs) involved in this process, we biochemically identified proteins bound to genomic and subgenomic SARS-CoV-2...
Zach H Gray,Damayanti Chakraborty,Reuben R Duttweiler et al. Zach H Gray et al.
MLL/KMT2A amplifications and translocations are prevalent in infant, adult, and therapy-induced leukemia. However, the molecular contributor(s) to these alterations are unclear. Here, we demonstrate that histone H3 lysine 9 mono- and di-met...
Ajinkya Patil,Amy R Strom,Joao A Paulo et al. Ajinkya Patil et al.
Intrinsically disordered regions (IDRs) represent a large percentage of overall nuclear protein content. The prevailing dogma is that IDRs engage in non-specific interactions because they are poorly constrained by evolutionary selection. He...
Tomohiro Hino,Satoshi N Omura,Ryoya Nakagawa et al. Tomohiro Hino et al.
SpCas9 and AsCas12a are widely utilized as genome-editing tools in human cells. However, their relatively large size poses a limitation for delivery by cargo-size-limited adeno-associated virus (AAV) vectors. The type V-F Cas12f from Acidib...
Florian Wimmers,Allison R Burrell,Yupeng Feng et al. Florian Wimmers et al.
The dynamics of immunity to infection in infants remain obscure. Here, we used a multi-omics approach to perform a longitudinal analysis of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in infants and young childr...
Joseph L Watson,Lara K Krüger,Ariel J Ben-Sasson et al. Joseph L Watson et al.
Polarized cells rely on a polarized cytoskeleton to function. Yet, how cortical polarity cues induce cytoskeleton polarization remains elusive. Here, we capitalized on recently established designed 2D protein arrays to ectopically engineer ...