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期刊名:Cell

缩写:CELL

ISSN:0092-8674

e-ISSN:1097-4172

IF/分区:42.5/Q1

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共收录本刊相关文章索引9608
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Christine K Rummel,Miriam Gagliardi,Ruhel Ahmad et al. Christine K Rummel et al.
Schizophrenia (SCZ) is a highly heritable mental disorder with thousands of associated genetic variants located mostly in the noncoding space of the genome. Translating these associations into insights regarding the underlying pathomechanis...
Li Li,Sarah Bowling,Sean E McGeary et al. Li Li et al.
Cellular lineage histories and their molecular states encode fundamental principles of tissue development and homeostasis. Current lineage-recording mouse models have insufficient barcode diversity and single-cell lineage coverage for profi...
Xiaofeng Qi,Qinli Hu,Nadia Elghobashi-Meinhardt et al. Xiaofeng Qi et al.
Wnt proteins are enzymatically lipidated by Porcupine (PORCN) in the ER and bind to Wntless (WLS) for intracellular transport and secretion. Mechanisms governing the transfer of these low-solubility Wnts from the ER to the extracellular spa...
Andrea C Wong,Ashwarya S Devason,Iboro C Umana et al. Andrea C Wong et al.
Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been formulated to explain the eti...
Adam L Boxer,Reisa Sperling Adam L Boxer
Alzheimer's disease (AD) research has entered a new era with the recent positive phase 3 clinical trials of the anti-Aβ antibodies lecanemab and donanemab. Why did it take 30 years to achieve these successes? Developing potent therapies fo...
Anand Bakshi,Fabio Echegaray Iturra,Andrew Alamban et al. Anand Bakshi et al.
Cytoplasmic divisions are thought to rely on nuclear divisions and mitotic signals. We demonstrate in Drosophila embryos that cytoplasm can divide repeatedly without nuclei and mitotic CDK/cyclin complexes. Cdk1 normally slows an otherwise ...
Dor Russ,Connor R Fitzpatrick,Paulo J P L Teixeira et al. Dor Russ et al.
Plant-associated microbiota can extend plant immune system function, improve nutrient acquisition and availability, and alleviate abiotic stresses. Thus, naturally beneficial microbial therapeutics are enticing tools to improve plant produc...
Marcin J Suskiewicz,Evgeniia Prokhorova,Johannes G M Rack et al. Marcin J Suskiewicz et al.
ADP-ribosylation is a ubiquitous modification of biomolecules, including proteins and nucleic acids, that regulates various cellular functions in all kingdoms of life. The recent emergence of new technologies to study ADP-ribosylation has r...
Terence Gall-Duncan,Jennifer Luo,Carla-Marie Jurkovic et al. Terence Gall-Duncan et al.
Expansions of repeat DNA tracts cause >70 diseases, and ongoing expansions in brains exacerbate disease. During expansion mutations, single-stranded DNAs (ssDNAs) form slipped-DNAs. We find the ssDNA-binding complexes canonical replication ...
Zijun Lan,Zihan Song,Zhijuan Wang et al. Zijun Lan et al.
Pollen-pistil interactions establish interspecific/intergeneric pre-zygotic hybridization barriers in plants. The rejection of undesired pollen at the stigma is crucial to avoid outcrossing but can be overcome with the support of mentor pol...