F Vanessa Loiacono,Ralph Bock
F Vanessa Loiacono
RNA polymerases (RNAPs) control the first step of gene expression in all forms of life by transferring genetic information from DNA to RNA, a process known as transcription. In this issue of Cell, Webster et al. and Wu et al. report three-d...
Jae-Hyun Yang,Motoshi Hayano,Luis A Rajman et al.
Jae-Hyun Yang et al.
James A Timmons,Charles Brenner
James A Timmons
Martin Pacesa,Oana Pelea,Martin Jinek
Martin Pacesa
Genome editing has been a transformative force in the life sciences and human medicine, offering unprecedented opportunities to dissect complex biological processes and treat the underlying causes of many genetic diseases. CRISPR-based tech...
Tuuli Lappalainen,Yang I Li,Sohini Ramachandran et al.
Tuuli Lappalainen et al.
Human genetics has emerged as one of the most dynamic areas of biology, with a broadening societal impact. In this review, we discuss recent achievements, ongoing efforts, and future challenges in the field. Advances in technology, statisti...
E Andrew Bennett,Qiaomei Fu
E Andrew Bennett
Growing evidence from archaic and early modern human genomes brings new insights to the emergence of modern humans. We recount recent information collected from ancient DNA studies that inform us about the evolutionary pathway to modern hum...
Tom van der Valk,Love Dalèn
Tom van der Valk
Genomic approaches have the potential to play a pivotal role in conservation, both to detect threats to species and populations and to restore biodiversity through actions. We here separate these approaches into two subdisciplines, vulnerab...
Doogab Yi,Janet E Mertz
Doogab Yi
In fall 1972, Paul Berg's laboratory published articles in PNAS describing two methods for constructing recombinant DNAs in vitro. He received half of the 1980 Nobel Prize in Chemistry for this landmark accomplishment. Here, we describe how...
Cell Editorial Team
Cell Editorial Team
Londa Schiebinger [0.03%]
隆达·谢宾格
Londa Schiebinger
Londa Schiebinger
Dr. Londa Schiebinger is an international leader on the intersection of sex, gender, and science. In this interview with Cell, she discusses the Gendered Innovations project, the persistent STEM gender gap, the importance of considering sex...