Xiaolin Huang,Yang Dan
Xiaolin Huang
Somatic and sympathetic tones fluctuate together seamlessly across daily behaviors. In this issue of Cell, Zhang et al. describe populations of spinal projecting neurons in the rostral ventromedial medulla (rVMM) that harmonize somatic moto...
Gut microbiome ecological topology as next-generation biomarkers for cancer immunotherapy [0.03%]
肠道微生物组生态拓扑将成为癌症免疫治疗的下一代生物标志物
Lijun Ning,Jie Hong
Lijun Ning
Numerous studies have evaluated the gut microbiome as a biomarker for predicting cancer immunotherapy, but the heterogeneity among different studies has hindered its applications. In this issue of Cell, Derosa et al. report a biomarker base...
Shinya Yamanaka [0.03%]
山中申彥
Shinya Yamanaka
Shinya Yamanaka
Dr. Shinya Yamanaka is recognized for his discovery of the induction of pluripotent stem cells from fibroblasts by a combination of defined factors. In this interview with Cell, he discusses the progress of the field, what's next for clinic...
Jennifer Lewis,Melina Schuh,Jacob H Hanna et al.
Jennifer Lewis et al.
The next 50 years of developmental biology will illuminate exciting new discoveries but are also poised to provide solutions to important problems society faces. Ten scientists whose work intersects with developmental biology in various cap...
Insoo Hyun
Insoo Hyun
Stem cells can be coaxed to self-organize into dynamic models of human development and early embryo formation. Despite their scientific promise, might widespread use of these technologies alter people's beliefs about what it means to be a h...
Jun Wu,Jianping Fu
Jun Wu
Developing functional organs from stem cells remains a challenging goal in regenerative medicine. Existing methodologies, such as tissue engineering, bioprinting, and organoids, only offer partial solutions. This perspective focuses on two ...
Amander T Clark,Janet Rossant,Robin Lovell-Badge
Amander T Clark
In the rapidly moving field of stem cell and embryo research, research questions often sit at the intersection of scientific inquiry and ethical considerations. The International Society for Stem Cell Research (ISSCR) produces guidelines to...
Parsing patterns: Emerging roles of tissue self-organization in health and disease [0.03%]
解析模式:组织自组织在健康和疾病中作用的新角色
Raul Ramos,Benjamin Swedlund,Anand K Ganesan et al.
Raul Ramos et al.
Patterned morphologies, such as segments, spirals, stripes, and spots, frequently emerge during embryogenesis through self-organized coordination between cells. Yet, complex patterns also emerge in adults, suggesting that the capacity for s...
Cell Editorial team
Cell Editorial team
Awe-inspiring developmental biology is all around us. In this 50th Anniversary focus issue, we celebrate developmental biology with content paying homage to the incredible progress the field has witnessed over the last five decades as well ...
Francesco Andreata,Chiara Laura,Micol Ravà et al.
Francesco Andreata et al.
Reversing CD8+ T cell dysfunction is crucial in treating chronic hepatitis B virus (HBV) infection, yet specific molecular targets remain unclear. Our study analyzed co-signaling receptors during hepatocellular priming and traced the trajec...