Cell Line: 2014-2024 [0.03%]
细胞系：2014-2024
Cell editorial team
Cell editorial team
Zhonghua Liu,Tsan Sam Xiao
Zhonghua Liu
Plasma membrane rupture during lytic cell death was previously believed to occur through passive osmosis that burst open the membrane. Recent publications, including one in this issue of Cell, suggest that plasma membrane rupture is an acti...
Cell after 50 [0.03%]
五十岁以后的细胞状态
John W Pham
John W Pham
Integration of 168,000 samples reveals global patterns of the human gut microbiome [0.03%]
整合168,000个样本揭示人类肠道微生物组的全球特征
Richard J Abdill,Samantha P Graham,Vincent Rubinetti et al.
Richard J Abdill et al.
The factors shaping human microbiome variation are a major focus of biomedical research. While other fields have used large sequencing compendia to extract insights requiring otherwise impractical sample sizes, the microbiome field has lack...
Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders [0.03%]
大规模并行报告基因检测研究八种精神疾病共有的遗传变异
Sool Lee,Jessica C McAfee,Jiseok Lee et al.
Sool Lee et al.
A meta-genome-wide association study across eight psychiatric disorders has highlighted the genetic architecture of pleiotropy in major psychiatric disorders. However, mechanisms underlying pleiotropic effects of the associated variants rem...
Receptor binding, structure, and tissue tropism of cattle-infecting H5N1 avian influenza virus hemagglutinin [0.03%]
禽源H5N1病毒血凝素受体结合、结构与组织嗜性研究
Hao Song,Tianjiao Hao,Pu Han et al.
Hao Song et al.
The ongoing circulation of highly pathogenic avian influenza (HPAI) A (H5N1) viruses, particularly clade 2.3.4.4b strains, poses a significant threat to animal and public health. Recent outbreaks in cattle highlight concerns about cross-spe...
A natural variant of COOL1 gene enhances cold tolerance for high-latitude adaptation in maize [0.03%]
COOL1基因自然变异通过增强冷耐受性促进高纬度地区玉米适应性的提高
Rong Zeng,Yiting Shi,Li Guo et al.
Rong Zeng et al.
Low temperature severely limits the growth, yield, and geographical distribution of maize (Zea mays L.). How maize adapts to cold climates remains largely unclear. Here, we identify a basic helix-loop-helix (bHLH) transcription factor, COLD...
Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease [0.03%]
元基因组指导的人体肠道微生物组、宿主和饮食暴露组的元蛋白质组学解开健康和炎症性肠病的标志物
Rafael Valdés-Mas,Avner Leshem,Danping Zheng et al.
Rafael Valdés-Mas et al.
Host-microbiome-dietary interactions play crucial roles in regulating human health, yet their direct functional assessment remains challenging. We adopted metagenome-informed metaproteomics (MIM), in mice and humans, to non-invasively explo...
An atlas of transcription initiation reveals regulatory principles of gene and transposable element expression in early mammalian development [0.03%]
转录起始图谱揭示了早期哺乳动物发育中基因和转座元件表达的调控原则
Marlies E Oomen,Diego Rodriguez-Terrones,Mayuko Kurome et al.
Marlies E Oomen et al.
Transcriptional activation of the embryonic genome (EGA) is a major developmental landmark enabling the embryo to become independent from maternal control. The magnitude and control of transcriptional reprogramming during this event across ...
Systems-level immunomonitoring in children with solid tumors to enable precision medicine [0.03%]
儿童实体瘤免疫监测的精准医疗水平系统免疫监视
Qi Chen,Binbin Zhao,Ziyang Tan et al.
Qi Chen et al.
Cancer is the leading cause of death from disease in children. Survival depends not only on surgery, cytostatic drugs, and radiation but also on systemic immune responses. Factors influencing these immune responses in children of different ...