Impact of CD34 positive cell dose in donor graft on the outcomes after haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide - A retrospective single-center study with a Japanese cohort [0.03%]
供者移植物中CD34阳性细胞剂量对移植后环磷酰胺联合单倍体外周血干细胞移植预后的影响-一项包含日本患者队列的单中心回顾性研究
Yumiko Maruyama,Hidekazu Nishikii,Naoki Kurita et al.
Yumiko Maruyama et al.
Background: Haploidentical peripheral blood stem cell transplantation (haplo-PBSCT) with post-transplant cyclophosphamide (PTCy) is an important therapeutic option for patients lacking an HLA-matched donor. However, the s...
Measurement of red cell, plasma and blood volume: Essential components of diagnostic and research studies of oxygen transport [0.03%]
红细胞、血浆和全血容量的测定：氧运输诊断和研究的重要组成部分
Marshall A Lichtman,Josef T Prchal
Marshall A Lichtman
Calcium flux alterations in erythrocytes from sickle cell mice: The relevance of mean corpuscular volume [0.03%]
异常血红蛋白小鼠红细胞钙稳态的变化:平均红细胞体积的意义
Luis E F Almeida,Meghann L Smith,Sayuri Kamimura et al.
Luis E F Almeida et al.
Red blood cells (RBC) from patients with sickle cell disease (SCD) have elevated calcium levels at baseline, which are further elevated upon deoxygenation. Here we examined baseline calcium levels and calcium flux in RBCs from a mouse model...
Clonal hematopoiesis and acquired genetic abnormalities of the red cell: An historical review [0.03%]
克隆性血液生成和获得性的红细胞遗传异常：历史回顾
Marshall A Lichtman
Marshall A Lichtman
Several syndromes affecting the red cell that mimic those induced by germline mutations may result from a somatic mutation that accompanies a myeloid malignancy. These syndromes are most notable in cases of myelodysplastic syndrome, but the...
Antineoplastic effects of pharmacological inhibitors of aurora kinases in CSF3RT618I-driven cells [0.03%]
靶向CSF3RT618I驱动的细胞中奥瑞梯激酶药理学抑制剂的抗肿瘤效果
Natália Sudan Parducci,Anali Del Milagro Bernabe Garnique,Keli Lima et al.
Natália Sudan Parducci et al.
Myeloproliferative neoplasms (MPN) are consolidated as a relevant group of diseases derived from the malfunction of the hematopoiesis process and have as a particular attribute the increased proliferation of myeloid lineage. Among these, ch...
First report of a patient with homozygous hemoglobin Ernz: Evidence to support a non-pathogenic variant [0.03%]
纯合子血红蛋白Ernz病例的首次报道：支持其为非致病突变的证据
Zohreh Shojaei,Maryam Abiri,Fatemeh Zafarghandi Motlagh et al.
Zohreh Shojaei et al.
Hemoglobin Ernz (Hb Ernz) is a missense variant in β-globin caused by a Threonine to Asparagine substitution at the 123rd amino acid position and HBB c.371C > A in gene level. Hb Ernz has been classified as Uncertain Significance (VUS) by ...
The role of PKC in X-ray-induced megakaryocyte apoptosis and thrombocytopenia [0.03%]
蛋白激酶C在X射线诱导的巨核细胞凋亡及血小板减少中的作用研究
Fanbi Meng,Shuang Chen,Chunliang Liu et al.
Fanbi Meng et al.
Thrombocytopenia is a critical complication after radiation therapy and exposure. Dysfunction of megakaryocyte development and platelet production are key pathophysiological stages in ionizing radiation (IR)-induced thrombocytopenia. Protei...
Hemalatha Sundaramoorthi,Weam Fallatah,Jabila Mary et al.
Hemalatha Sundaramoorthi et al.
Thrombopoiesis is the production of platelets from megakaryocytes in the bone marrow of mammals. In fish, thrombopoiesis involves the formation of thrombocytes without megakaryocyte-like precursors but derived from erythrocyte thrombocyte b...
Severe clinical picture in a cohort of six Brazilian children with hemoglobin Sβ-thalassemia IVS-I-5 G>A [0.03%]
巴西六例内含子I-5(G>A)杂合子突变的HbSβ地中海贫血患儿的临床特征
Marcos Borato Viana,Érica Louback Oliveira,André Rolim Belisário
Marcos Borato Viana
Outcome of first or second transplantation using unrelated umbilical cord blood without ATG conditioning regimen for pediatric bone marrow failure disorders [0.03%]
无ATG预处理方案下无关脐带血首次或再次移植治疗儿童骨髓衰竭性疾病结局分析
Xia Chen,Fang Liu,Yuanyuan Ren et al.
Xia Chen et al.
Background: Unrelated umbilical cord blood transplantation (UCBT) for bone marrow failure (BMF) disorders using conditioning regimens without Anti-Thymocyte Globulin (ATG) has been used as an alternative transplantation f...