Managing heavy menstrual bleeding in adolescents with bleeding disorders: Outcomes from a pragmatic LMIC approach [0.03%]
Sandhya Gupta,Nita Radhakrishnan,Archit Pandharipande et al.
Sandhya Gupta et al.
Background: Heavy menstrual bleeding (HMB) a common manifestation of bleeding disorders in adolescents contributes to anemia, transfusions, and impaired quality-of-life (QOL). Evidence supporting practical management stra...
HbS-β thalassemia mimicking HbSS on DdeI RFLP: Report of a pitfall circumventable by Sanger sequencing and parental testing [0.03%]
Diksha Dev Yadav,Jasbir Kaur Hira,Sanjeev Chhabra et al.
Diksha Dev Yadav et al.
MRI-derived hepatic fat and its clinical correlates in non-transfusion-dependent thalassemia: a cross-sectional study [0.03%]
非输血依赖性地中海贫血患者肝脏脂肪磁共振值及其临床相关因素：横断面研究
Antonella Meloni,Laura Pistoia,Paolo Ricchi et al.
Antonella Meloni et al.
We quantified hepatic fat fraction (FF) by magnetic resonance imaging (MRI) in non-transfusion-dependent thalassemia (NTDT) patients, and we evaluated its associations with demographic, clinical, and biochemical parameters, tissue iron over...
Inflammatory markers in sickle cell disease during vaso-occlusive crisis [0.03%]
镰状细胞病急性血管阻塞危象期的炎症标志物变化
Kamal Kumar Meher,Pradeep Kumar Mohanty,Satyabrata Meher
Kamal Kumar Meher
Sickle cell disease (SCD) is a monogenic blood disorder in which vaso-occlusive crises (VOC) are the main cause of hospitalization. Along with vascular adhesion, inflammation plays a central role in VOC. This study compared inflammatory and...
Newborn screening for sickle cell disease in Angola: Implementation challenges and emerging data on hemoglobinopathy prevalence [0.03%]
安哥拉镰状细胞病新生儿筛查的实施挑战及血红蛋白病患病率的数据公布
Miguel Brito,Catarina Ginete,Mariana Jacinto et al.
Miguel Brito et al.
Sickle Cell Disease (SCD) is an autosomal recessive disorder with a substantial global burden. Despite its particularly high incidence in sub-Saharan Africa, early diagnosis remains limited in many countries. The objective of this study was...
Exercise training adaptations on cardiorespiratory fitness and quality of life of patients with sickle cell disease: A systematic review [0.03%]
锻炼训练对镰状细胞病患者心肺功能和生活质量影响的系统评价
Gilson Dorneles,Igor da Silva,Bruna Marmett
Gilson Dorneles
This study aims to assess the effect of endurance training on cardiorespiratory adaptations and health-related quality of life (HRQoL) of patients with sickle cell disease (SCD). Three databases (Pubmed, Embase and Web of Science) were sear...
Clinical outcomes and health-system challenges in congenital afibrinogenemia: a single-centre prospective case series [0.03%]
先天性无纤维蛋白原血症的临床转归和卫生系统挑战：一项单中心前瞻性病例系列研究
Nita Radhakrishnan,Savitri Singh,Archit Pandharipande et al.
Nita Radhakrishnan et al.
Background: Congenital afibrinogenemia is a very rare bleeding disorder which is often life threatening. Data are scarce, and only 29 Indian cases have been officially reported to World Federation of Hemophilia, mostly as...
Kiranmye Reddy,Jonathan D Fish,Jennifer Eng et al.
Kiranmye Reddy et al.
Purpose: To assess the prevalence and severity of transfusion-associated iron overload (IO) in childhood cancer survivors (CCS). Patients and methods: ...
Relationship between PCT, CRP, and IL-6 and postoperative delirium in ICU patients and its influencing factors [0.03%]
ICU患者术后谵妄与PCT、CRP和IL-6的关系及其影响因素
Huayong Song,Lijing Shen,Wen Sun et al.
Huayong Song et al.
Objective: To investigate the relationship of procalcitonin (PCT), C-reactive protein (CRP), and interleukin-6 (IL-6) with postoperative delirium (POD) in intensive care unit (ICU) patients, and to identify influencing fa...
Ex vivo culture of hematopoietic stem and progenitor cells with platelet lysate: Investigating proliferation and erythroid-megakaryocytic lineage effects [0.03%]
含血小板 lysate 的体外造血干细胞和祖细胞培养：探究其增殖及红系-巨核系分化的影响
Farnaz Pirsavabi,Zahra Najafi,Mohammad Ebrahimi Siahboomi et al.
Farnaz Pirsavabi et al.
Hematopoietic stem and progenitor cells (HSPCs) are valuable for therapies and research due to their self-renewal and differentiation abilities. The ex vivo culture of these cells necessitates conditions that maintain their unique propertie...