Endurance training and hydroxyurea have synergistic effects on muscle function and energetics in sickle cell disease mice
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Sickle cell disease (SCD) is an hemoglobinopathy resulting in the production of an abnormal Hb (HbS) which can polymerize in deoxygenated conditions, leading to the sickling of red blood cells (RBC). These alterations can decrease the oxygen-carrying capacity ... ...
