Rare bleeding disorders: Real-world data from a Spanish tertiary hospital [0.03%]
罕见出血障碍:来自西班牙三级医院的真实世界数据
Daniel Martínez-Carballeira,Alberto Caro,Ángel Bernardo et al.
Daniel Martínez-Carballeira et al.
Introduction: Due to their low prevalence, rare bleeding disorders (RBDs) remain poorly characterized. Aim: To gain insight of RBDs thr...
Investigation of the cytotoxicity, genotoxicity and antioxidant prospects of JM-20 on human blood cells: A multi-target compound with potential therapeutic applications [0.03%]
JM-20对人血细胞的细胞毒性和致突变性的研究及其作为多靶点化合物的抗氧化前景和潜在治疗应用
Fernanda DAvila da Silva,Maria Eduarda de Andrade Galiciolli,Ana Carolina Irioda et al.
Fernanda DAvila da Silva et al.
JM-20 is a 1,5-benzodiazepine compound fused to a dihydropyridine fraction with different pharmacological properties. However, its potential toxic effects on blood cells have not yet been reported. Thus, the present study aimed to investiga...
A comparative study of two routinely used protocols for ex vivo erythroid differentiation [0.03%]
两种常规使用的红细胞体外分化方案的比较研究
Auria Godard,Robert Seute,Alexandra Grimaldi et al.
Auria Godard et al.
Background: Erythropoiesis is a complex developmental process in which a hematopoietic stem cell undergoes serial divisions and differentiates through well-defined stages to give rise to red blood cells. Over the last dec...
Regarding γ' fibrinogen levels as a biomarker of COVID-19 respiratory disease severity [0.03%]
关于将γ'纤维蛋白原水平作为COVID-19呼吸疾病严重程度的生物标志物的问题
Lucy Z Kornblith,Bindhya Sadhanandhan,Sreepriya Arun et al.
Lucy Z Kornblith et al.
Unveiling mortality risk factors in paediatric sickle cell disease patients during acute crises in the Democratic Republic of the Congo [0.03%]
在刚果民主共和国小儿缺血病患者急性危象期间揭示死亡风险因素
Paul Muteb Boma,Stéphanie Luntadila Ngimbi,Junior Makiese Kindundu et al.
Paul Muteb Boma et al.
Sickle cell disease (SCD) is a significant health burden in the Democratic Republic of the Congo (DRC). This study aims to identify predictive factors of mortality in SCD children admitted to emergency care in Lubumbashi, DRC. We performed ...
Effect of voxelotor on murine bone marrow and peripheral blood with hematopoietic progenitor cell mobilization for gene therapy of sickle cell disease [0.03%]
voxelotor对造血祖细胞动员的小鼠骨髓和外周血的影响基因治疗方案用于治疗镰状细胞疾病
Avital Mendelson,Yunfeng Liu,Weili Bao et al.
Avital Mendelson et al.
In preparation for hematopoietic stem cell mobilization and collection, current ex vivo gene therapy protocols for sickle cell disease require patients to undergo several months of chronic red cell transfusion. For health care equity, alter...
Regarding γ' fibrinogen levels as a biomarker of COVID-19 respiratory disease severity [0.03%]
关于将γ'纤维蛋白原水平作为COVID-19呼吸道疾病严重程度的生物标志物的问题
Sangsang Wang,Diao Yu,Junwu Zhang
Sangsang Wang
Bio-net dataset: AI-based diagnostic solutions using peripheral blood smear images [0.03%]
生物网络数据集:使用周边血涂片图像的AI基础诊断方案
Usman Ali Shams,Isma Javed,Muhammad Fizan et al.
Usman Ali Shams et al.
Peripheral blood smear examination is one of the basic steps in the evaluation of different blood cells. It is a confirmatory step after an automated complete blood count analysis. Manual microscopy is time-consuming and requires profession...
Unmasking the morphological alteration of erythrocytes among women suffering from PCOS [0.03%]
揭开患有PCOS的女性红细胞形态改变的面纱
Sutithi Dey,Ipsita Chakraborty,Payel Biswas et al.
Sutithi Dey et al.
Dyslipidemia is frequently observed in polycystic ovarian syndrome (PCOS). Changes in plasma lipid levels potentially alter erythrocyte membrane lipid composition due to lack of inbuilt lipid synthesis machinery. Therefore, development of m...
Characterization of a cohort of Angolan children with sickle cell anemia treated with hydroxyurea [0.03%]
接受羟基脲治疗的安哥拉患镰状细胞贫血症儿童群体的特征分析
Brígida Santos,Catarina Ginete,Elisângela Gonçalves et al.
Brígida Santos et al.
Background: Sickle Cell Anemia (SCA) is a monogenic disease, although its severity and response to treatment are very heterogeneous. Objectives: ...