Red blood cell pyruvate kinase properties in Townes and Berkeley sickle cell disease mouse models - Of mice and men [0.03%]
Townes和Berkeley型镰状细胞病小鼠模型红细胞丙酮酸激酶的性质-谈小鼠与人
Marissa J M Traets,Titine J J Ruiter,Charles Levine et al.
Marissa J M Traets et al.
Pyruvate kinase (PK), a key ATP-generating enzyme in glycolysis, is a target for novel sickle cell disease (SCD) therapies. Enhancing PK activity lowers 2,3-diphosphyglycerate (2,3-DPG), increases adenosine triphosphate (ATP), and may preve...
Short- and long-term alterations of hematopoietic cell lineages in rats with congenital iron deficiency [0.03%]
先天性缺铁大鼠血细胞谱系的短期和长期改变
Anthony Babu,Zachary R Smith,Narmin Mukhtarova et al.
Anthony Babu et al.
Data support that fetal iron delivery is prioritized to hemoglobin in erythrocytes (RBC). Iron deficiency (ID) during pregnancy can cause congenital ID, i.e., low fetal iron acquisition. Because how congenital ID impacts other fetal hematop...
Marked microcytosis and increased transferrin saturation: Think about variants in SLC11A2 (DMT1) [0.03%]
SLC11A2(DMT1)基因突变导致的血红素合成异常：不宜单凭发现血清转铁蛋白饱和度增加和靶器官损伤而诊断铁粒幼细胞贫血
Alexandre Raynor,Katell Peoc&#x;h,Camille Boi et al.
Alexandre Raynor et al.
Congenital microcytic anemias are rare diseases associated with decreased hemoglobin synthesis and red blood cells of low corpuscular volume. DMT1/NRAMP2 is a highly conserved divalent cation transporter encoded by the SLC11A2 gene, express...
Corrigendum to "Clinical utility of relative telomere length analysis in pediatric bone marrow failure" [Blood Cells Mol. Dis. 109 (2024) 102882] [0.03%]
关于“儿科骨髓衰竭相对端粒长度分析的临床应用”一文的勘误[Blood Cells Mol. Dis. 109 (2024) 102882]
Shilpa Amatya,Prateek Bhatia,Sudhanshi Raina et al.
Shilpa Amatya et al.
Published Erratum
Blood cells, molecules & diseases. 2025 Feb:110:102899. DOI:10.1016/j.bcmd.2024.102899 2025
Identification of Nfel1a and Nfel3 as novel regulators for zebrafish thrombopoiesis [0.03%]
Nfel1a和Nfel3是斑马鱼巨核细胞产板型血小板生成的新调节因子
Weam Fallatah,Sanchi Dhinoja,Ayah Al Qaryoute et al.
Weam Fallatah et al.
In mammalian hematopoiesis, megakaryocytes mature and become polyploid in the bone marrow before releasing platelets into circulation. In contrast, fish produce thrombocytes in kidney marrow, where young thrombocytes undergo maturation in c...
Hemophagocytic lymphohistiocytosis associated with immune checkpoint inhibitor use: A review of the current knowledge and future directions [0.03%]
与免疫检查点抑制剂使用相关的噬血细胞综合征淋巴组织细胞增生症：当前知识和未来方向的回顾
Charlotte S Walmsley,Zachary Schoepflin,Charlotte De Brabandt et al.
Charlotte S Walmsley et al.
Hemophagocytic lymphohistiocytosis (HLH) is a severe and often lethal inflammatory syndrome characterized by excessive immune activation leading to fever, cytopenias, and multiorgan involvement. Immune checkpoint inhibitors (ICIs) are centr...
Further biological characterization of small molecules UM171 and SR1: In vitro effects on three hematopoietic cell populations from human cord blood [0.03%]
UM171和SR1的进一步生物学表征及其对人脐带血三种造血细胞群的体内影响
Patricia Flores-Guzman,Aranxa Torres-Caballero,Hector Mayani
Patricia Flores-Guzman
Small molecules UM171 and SR1 have already been taken into clinically-oriented protocols for the ex vivo expansion of hematopoietic stem (HSCs) and progenitor (HPCs) cells. In order to gain further insight into their biology, in the present...
Growth hormone is involved in GATA1 gene expression via STAT5B in human erythroleukemia and monocytic cell lines [0.03%]
生长激素通过STAT5B参与人红白血病及单核细胞系中GATA1基因的表达调控
Mana Mitsutani,Mei Yokoyama,Hiromi Hano et al.
Mana Mitsutani et al.
GATAs are a family of transcription factors consisting of six members. Particularly, GATA1 and GATA2 have been reported to promote the development of erythrocytes, megakaryocytes, eosinophils, and mast cells. However, little information is ...
Phenotypic and genotypic evaluation of bleeding diagnostic dilemmas: Two case studies [0.03%]
出血诊断难题的表型和基因型评估：两例研究报告
Sean X Gu,Ayesha Butt,Vincent P Schulz et al.
Sean X Gu et al.
Inherited platelet disorders (IPDs) are a heterogeneous group of conditions that present significant challenges in diagnosis and management. Here, we report two cases of patients presenting with clinically significant bleeding but with uncl...
Corrigendum to "Outpatient ATG-free hematopoietic transplantation for severe aplastic anemia in limited-resource environments offers excellent results: Data from a single LATAM center" [Blood Cells, Mol. Dis. 109 (2024) 102885] [0.03%]
对“在资源有限的环境中，门诊ATG-free造血移植治疗重度再生障碍性贫血可获得优异结果：来自单个拉丁美洲中心的数据”[《血液细胞、分子疾病》109 (2024) 102885] 的勘误
José Carlos Jaime-Pérez,Mariana González-Treviño,Andrés Gómez-De León et al.
José Carlos Jaime-Pérez et al.
Published Erratum
Blood cells, molecules & diseases. 2025 Feb:110:102886. DOI:10.1016/j.bcmd.2024.102886 2025