SOX9 is part of a combinatorial marker that reveals early development and embryological origins of the mouse brown adipose tissue depots [0.03%]
SOX9是一个组合标记物的一部分，可揭示小鼠棕色脂肪组织的早期发育和胚胎起源
Ava E Brent,Rika Chan,Vaishnavi Sirkay et al.
Ava E Brent et al.
Brown adipose tissue (BAT) is a mammalian thermogenic tissue that helps to maintain body temperature and provides important metabolic functions. Most brown adipocytes are located in structures called depots, the developmental origins of whi...
Gonadal development and gene expression in the leopard gecko during temperature-dependent sex determination [0.03%]
温度依赖性性别决定下豹斑守宫生殖腺发育和基因表达特点的研究
Shinnosuke Okano,Yukima Yoshizawa,Shouei Nobuchi et al.
Shinnosuke Okano et al.
Temperature-dependent sex determination (TSD) is prevalent in reptiles, yet its molecular mechanisms, particularly in squamates, remain poorly understood. This study presents the first comprehensive histological and transcriptomic analysis ...
The Halloween gene shadow is involved in embryonic development and postembryonic molting in the spider Parasteatoda tepidariorum [0.03%]
万圣节基因在模式蜘蛛胚胎发育及若虫蜕皮中的功能研究
Denise Klinkenbuß,Sandra Treffkorn,Georg Mayer et al.
Denise Klinkenbuß et al.
Ecdysteroids are key hormones that regulate molting and developmental processes in arthropods, including insect metamorphosis. Understanding the molecular roles of the genes involved in ecdysteroid biosynthesis could provide crucial insight...
In vitro plasticity between ureteric epithelial and distal nephron identity and maturity is controlled by extracellular signals [0.03%]
尿管上皮细胞和远端肾小管之间的身份和成熟度的可塑性受外在信号控制
Pamela Kairath,Pei Xuan Er,Sean Wilson et al.
Pamela Kairath et al.
Several studies have described human pluripotent stem cell (hPSC)-derived ureteric epithelium, which in the embryo arises from the nephric duct and forms the collecting ducts of the kidney. However, hPSC-derived distal nephron epithelium ca...
Identification of evolutionary conserved and diverged regulatory elements of embryonic Msx1 expression among amniote species via 3D-genome analyses and in vivo assays [0.03%]
利用三维基因组分析和体内实验鉴定顶小骨蛋白1在羊膜动物胚胎表达中保守与分化出的调控元件
Yoshio Wakamatsu,Yukiko U Inoue,Shyu Manabe et al.
Yoshio Wakamatsu et al.
The Msx1 gene encodes a homeobox transcription factor that regulates numerous patterning events during the development of organs such as the limb bud and jaw primordium. In craniofacial development, Msx1 is involved not only in the proximal...
High-Sensitivity In Situ Detection of Sox21 Reveals Transcript Asymmetry from the Zygote Stage [0.03%]
高灵敏性原位检测SOX21揭示了从受精卵阶段开始的转录不对称性
Estefania Sanchez-Vasquez,Gyda Nawarungruang,Maciej Meglicki et al.
Estefania Sanchez-Vasquez et al.
The first lineage decision in mammalian development segregates embryonic and extra-embryonic fates, yet the timing of this specification remains under debate. While our previous lineage tracing studies in mice and human suggested that this ...
Deciphering the Single-Cell Transcriptomic Atlas of Donkey (Equus asinus) Gonad Development in Early Gestation [0.03%]
用于早期妊娠时期驴（Equus asinus）生殖腺发育的单细胞转录组图谱解析
Yadan Jin,Huajie Zhang,Ruixue Ma et al.
Yadan Jin et al.
In donkey reproduction, the extended reproductive cycle is a pivotal factor contributing to the low reproductive rate. Gonadal development represents a highly complex biological process that involves sex determination and subsequent progres...
Did the evolution of multiple microchromosomes help save bird and other dinosaurs from extinction? [0.03%]
多条微染色体的进化帮助鸟类和其他恐龙免于灭绝了吗？
Darren K Griffin,Rafael Kretschmer,Denis M Larkin et al.
Darren K Griffin et al.
Birds currently number ∼11,000 species and, despite enormous biodiversity, have numerous class-specific characteristics including feathers, flight, nesting, brooding, longevity and a very distinctive karyotype. Central to several academic ...
Tbx genes influence early gene expression and photoreceptor patterning in the chick retina [0.03%]
T盒基因影响鸡视网膜早期基因表达和光感受器的模式化
Monika Ayten,Heer N V Joisher,Chaitra Prabhakara et al.
Monika Ayten et al.
The retina, our sensory organ for vision, displays distinct photoreceptor distributions and can have a specialized region for high visual acuity. The establishment of these spatial patterns during development depends on regionally restricte...
Molecular Regulation of Telomeric Elongation and TERT Splicing in Planarians [0.03%]
涡虫染色体端粒延长及TERT拼接的分子调控
William Diaz,Claudia M Arenas-Gomez
William Diaz
Planarians, flatworms renowned for their extraordinary regenerative capacity, depend on a population of adult pluripotent stem cells known as neoblasts. Unlike most adult stem cells in mammals, neoblasts maintain sustained telomerase activi...