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In vitro plasticity between ureteric epithelial and distal nephron identity and maturity is controlled by extracellular signals

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Several studies have described human pluripotent stem cell (hPSC)-derived ureteric epithelium, which in the embryo arises from the nephric duct and forms the collecting ducts of the kidney. However, hPSC-derived distal nephron epithelium can also adopt a urete... ...