Sulfur signalling in Saccharomyces cerevisiae: From H2S to S-persulfidation [0.03%]
酿酒酵母中的硫信号：从H2S到S-双硫化修饰
Damián Ramírez-Robles,Emilio Espinoza-Simón,Marijose López-Miranda et al.
Damián Ramírez-Robles et al.
Hydrogen sulfide (H2S) is a gasotransmitter that regulates multiple cellular processes, such as carbon metabolism, endoplasmic reticulum stress response, redox homeostasis, and cellular survival. Saccharomyces cerevisiae is one of the few o...
Myoglobin leaching into the serum of IDA mice is associated with elevated sGC activation under anemic conditions that correlates with increased myoglobin expression [0.03%]
缺铁性贫血小鼠肌红蛋白浸出与升高的sGC激活及与增加的肌红蛋白数量有关
Arnab Ghosh,Nupur K Das,Mamta P Sumi et al.
Arnab Ghosh et al.
Our earlier study showed that sGC is critical for myoglobin (Mb) heme-maturation, while iron restriction is known to increase Mb expression which under anemic conditions may suggest an increase in heme-free Mb. We analyzed mice tissues to d...
Prognostic and monitoring relevance of systemic nitric oxide in patients with colon cancer [0.03%]
结肠癌患者全身一氧化氮的预后及监测价值
Rania-Sihem Boussa,Manel Amri,Imene Soufli et al.
Rania-Sihem Boussa et al.
Reliable and minimally invasive biomarkers are needed for early detection, prognosis, and monitoring of colon cancer (CC). The aim of our study was to evaluate the role of systemic nitric oxide (NO) in inflammation and tumor progression and...
Compartment-specific nitric oxide signaling in mouse cardiac endothelial cells: Intra- and extracellular measurements and the impact of cryopreservation [0.03%]
小鼠心内皮细胞中特定隔室的硝酸氧化物信号传导：冷冻保存的影响及细胞内外测量值
Elham Ashrafi,Janet A W Elliott
Elham Ashrafi
Nitric oxide (NO) produced by endothelial cells plays a central role in regulating vascular tone, blood flow, and inflammatory responses. Although NO freely diffuses across cell membranes, intracellular and extracellular NO-related signals ...
The role of nitric oxide in inflammation, tumor microenvironment, and cancer therapy [0.03%]
一氧化氮在炎症、肿瘤微环境和癌症治疗中的作用
Akhil Nair,Harishkumar Madhyastha,B C Revanasiddappa et al.
Akhil Nair et al.
Nitric oxide (NO) is a widespread signaling molecule which has far-reaching effects in cellular physiology and pathophysiology, especially in cancer biology. Its actions are concentration-dependent where low concentrations facilitate tumor ...
PRMT1 regulates glioblastoma stemness and immunosuppression via nitric oxide metabolism: Multi-cohort analysis and experimental validation [0.03%]
脯氨酰-l-甲基转移酶a通过一氧化氮代谢调控胶质母细胞瘤干细胞特性及免疫抑制：多队列分析和实验验证
Kun Xue,Ya Gao,Caifeng Ma et al.
Kun Xue et al.
Background: Glioblastoma is the most common primary malignant brain tumor with poor prognosis. The immunosuppressive microenvironment and cancer stem cells (CSCs) drive therapeutic resistance. The role of nitric oxide (NO...
The roles of hydrogen sulfide and reactive sulfur species in bacterial life within the human body [0.03%]
人体内细菌生命活动中的硫化氢和反应型硫化合物的作用
Shouta Nonoyama,Takayuki Shimizu,Shinji Masuda
Shouta Nonoyama
We summarize current knowledge on the roles of hydrogen sulfide (H2S) and reactive sulfur species (RSS) in bacterial strategies for survival and colonizing within the human body. Bacteria inhabiting the human body utilize H2S, derived from ...
Architectural modulation of polymeric hydrogen sulfide donors: Structure-responsive materials for controlled therapeutics [0.03%]
基于结构响应的聚硫化氢材料用于可控治疗
Vivek Pandey,Nikky Sharma,Tejasvi Pandey
Vivek Pandey
Hydrogen sulfide (H2S), once regarded merely as a malodorous and toxic gas, has emerged as a vital endogenous signaling molecule with multifaceted physiological roles, encompassing neuromodulation, vasorelaxation, cytoprotection, and the re...
Stable isotope measurement of in vivo nitric oxide production in health and disease: an updated systematic review and meta-analysis [0.03%]
体内一氧化氮生成的稳定同位素测定法在健康和疾病中的应用：系统回顾与meta分析更新
Thomas Loftus,Jonas Benjamim,Mauro Vaccarezza et al.
Thomas Loftus et al.
Background: Nitric oxide (NO) is involved in the regulation of vascular, immune and metabolic functions. Physiological modelling of stable isotope tracers provides an accurate method to measure whole-body NO production in...
Analytic performance characteristics of the chemical-reduction gas phase-chemiluminescence assay for the quantification of nitric oxide metabolites [0.03%]
化学还原气相 chemi luminescence 定量测定一氧化氮代谢产物的性能分析
Michelle Menon Miyake,Ipsita Mohanty,Sylvia N Michki et al.
Michelle Menon Miyake et al.
Nitric oxide metabolites (NOm) in biological fluids have been widely used as surrogate markers to inform changes in nitric oxide-mediated signaling, which is critical for many biological functions. One method for quantifying NOm employs che...