Myoglobin leaching into the serum of IDA mice is associated with elevated sGC activation under anemic conditions that correlates with increased myoglobin expression
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Our earlier study showed that sGC is critical for myoglobin (Mb) heme-maturation, while iron restriction is known to increase Mb expression which under anemic conditions may suggest an increase in heme-free Mb. We analyzed mice tissues to determine the link be... ...