A N Tintu,F A C le Noble,E V Rouwet
A N Tintu
Low-birth-weight babies have an increased risk of cardiovascular disease (CVD) in later life. The authors hypothesize that fetal hypoxia alters the structure and function of the developing cardiovascular system resulting in CVD. They invest...
Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis [0.03%]
脓毒症患者血浆内皮素-1和肾上腺髓质素水平及其相互作用的研究
Philipp Schuetz,Mirjam Christ-Crain,Nils G Morgenthaler et al.
Philipp Schuetz et al.
Plasma levels of endothelin-1 (ET-1) and adrenomedullin (ADM), two opposingly acting peptides, correlate with mortality in endotoxemia, but their measurement is cumbersome. New sandwich assays have been introduced that measure more stable p...
Glutathione-S-transferase protects against oxidative injury of endothelial cell tight junctions [0.03%]
谷胱甘肽-s-转移酶保护内皮细胞紧密连接免受氧化损伤
Y Xu,B Gong,Y Yang et al.
Y Xu et al.
Oxidative damage of endothelial tight junction permeability is involved in the pathophysiology of a variety of vascular diseases. The authors studied the role of the antioxidant enzyme, human glutathione-S-transferase A4-4 (hGSTA4-4), in re...
Both senescence and apoptosis induced by deprivation of growth factors were inhibited by a novel butyrolactone derivative through depressing integrin beta4 in vascular endothelial cells [0.03%]
缺因子诱导的衰老和凋亡通过新型丁内酯衍生物抑制血管内皮细胞整合素β4表达而被抑制
Weiwei Wang,Xia Liu,Yun Zhang et al.
Weiwei Wang et al.
Both senescence and apoptosis of vascular endothelial cells (VECs) are involved in the development of cardiovascular diseases, including atherosclerosis. To understand the association between senescence and apoptosis in vascular endothelial...
gamma-Aminbuturic acid A receptor mitigates homocysteine-induced endothelial cell permeability [0.03%]
γ-氨基丁酸A受体通过减少同型半胱氨酸诱导的内皮细胞通透性发挥神经保护作用
Neetu Tyagi,Karni S Moshal,Suresh C Tyagi et al.
Neetu Tyagi et al.
Many cerebrovascular disorders are accompanied by an increased homocysteine (Hcy) levels. We have previously shown that acute hyperhomocysteinemia (HHcy) leads to an increased microvascular permeability in the mouse brain. Hcy competitively...
A novel methodology to probe endothelial differential gene expression profile reveals novel genes [0.03%]
一种探测内皮细胞差异基因表达谱的新方法揭示了新的基因
Yi Shen,Einar Wilder-Smith,Esther Yu et al.
Yi Shen et al.
Endothelial dysfunction is a major feature of vascular diseases. A practical, minimally invasive method to effectively "probe" gene transcription for an individual patient's endothelium has potential to "customize" assessment for an individ...
Transcriptome of angiopoietin 1-activated human umbilical vein endothelial cells [0.03%]
血管生成素1活化的人脐静脉内皮细胞转录组分析
N A Abdel-Malak,R Harfouche,S N A Hussain
N A Abdel-Malak
Angiopoietin 1 (Ang-1) is the main ligand for endothelial cell-specific tyrosine kinase (Tie-2) receptors and it promotes migration and proliferation and inhibits apoptosis and vascular leakage. The exact mechanisms through which the Ang-1 ...
Role of ligand-specific integrins in endothelial cell alignment and elongation induced by cyclic strain [0.03%]
周期性拉伸诱导的内皮细胞排列和伸长中的配体特异性整联蛋白的作用
Yo Hirayama,Bauer E Sumpio
Yo Hirayama
Ligand-specific integrins are thought to play a critical role in regulating multiple biological processes. However, the mechanisms by which ligand-specific integrins mediate external stimuli and activate intracellular signaling pathways rem...
Low shear stress-induced interleukin-8 mRNA expression in endothelial cells is mechanotransduced by integrins and the cytoskeleton [0.03%]
低剪切应力引起的内皮细胞中IL-8的mRNA表达由整合素和细胞骨架介导转换而来
Min Cheng,Jiang Wu,Xiaoheng Liu et al.
Min Cheng et al.
Shear stress is thought to be important in maintaining vascular homeostasis and regulating vascular remodeling. The authors have previously shown that low shear stress increases interleukin (IL)-8 gene expression in endothelial cells. Howev...
The importance of electron microscopy in the study of capillary endothelial cells: an historical review [0.03%]
电子显微镜在毛细血管内皮细胞研究中的重要性：历史回顾
Beatrice Nico,Enrico Crivellato,Domenico Ribatti
Beatrice Nico
The second half of the 20th century has witnessed the birth and growth of biological ultrastructural research in which electron microscopy plays a crucial role. The electron microscope has contributed greatly to biology and medicine, as is ...