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Low shear stress-induced interleukin-8 mRNA expression in endothelial cells is mechanotransduced by integrins and the cytoskeleton

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Shear stress is thought to be important in maintaining vascular homeostasis and regulating vascular remodeling. The authors have previously shown that low shear stress increases interleukin (IL)-8 gene expression in endothelial cells. However, the detailed eve... ...