Enhancing Chemotherapy for Colorectal Cancer: EGFR-Conjugated Ferritin Nanocages for Targeted Doxorubicin Delivery [0.03%]
用于结直肠癌化疗的EGFR连接的铁蛋白纳米笼携带多柔比星疗法增强研究
Fatemeh Zali,Mohammad Ahmadi,Mohammad Ahmadyousefi et al.
Fatemeh Zali et al.
Biomimetic nanoparticles, exemplified by ferritin, have emerged as a novel approach in drug delivery systems, designed to improve both the biocompatibility of drugs and their targeting. The clinical application of doxorubicin (Dox) is imped...
Research progress of treating ulcerative colitis and colon cancer by using oral colon targeted drug delivery system based on polymer micelles [0.03%]
基于聚合物胶束的口服结肠定位递药系统治疗溃疡性结肠炎和结肠癌的研究进展
Shuangshuang Li,Te Li,Xueni Wang et al.
Shuangshuang Li et al.
Ulcerative colitis (UC) and colon cancer (CC) represent significant global health burdens. Current first-line chemotherapeutic agents, including capecitabine, oxaliplatin, and irinotecan, face two principal limitations: poor tumor specifici...
Angiopep-2 modified naringin nanoparticles for Alzheimer's disease therapy overcoming BBB [0.03%]
用于治疗阿尔茨海默病的Angiopep-2修饰柚皮素纳米粒克服血脑屏障
Jing Jiang,Yue Xing,Shumeng Liu et al.
Jing Jiang et al.
Naringin (4',5,7-trihydroxyflavanone-7-rhamnoglucoside, NG), a potential treatment for Alzheimer's disease (AD), has strong neuroprotective effects but is limited by poor solubility, low bioavailability, and limited brain accumulation. To a...
Correction [0.03%]
改正通知书
Published Erratum
Journal of drug targeting. 2025 May 30:1. DOI:10.1080/1061186X.2025.2513758 2025
Engineered Salmonella Carrying siRNA-PD-1 Shrinks orthotopically implanted Bladder Cancer in Rats [0.03%]
工程改造的沙门氏菌携带siRNA-PD-1缩小异位移植到大鼠体内的膀胱癌肿瘤
Qizhong Shi,Jiaxin Geng,Lulu Han et al.
Qizhong Shi et al.
Background Currently, the application of engineered bacteria in tumor treatment has received increasing attention. It has been proved that Bacillus Calmette-Guerin (BCG) can effectively treat bladder cancer (BC). In addition, immune checkpo...
Improved Antidiabetic Potential of Quercetin-Loaded Chitosan-Lecithin Nanoparticles for Effective Glycemic Control [0.03%]
一种有效的降糖控糖载黄酮壳聚素-卵磷脂纳米粒的抗糖尿病潜力研究
Mohammad Zaki Ahmad,Kalyani Pathak,Afroze Alam et al.
Mohammad Zaki Ahmad et al.
IntroductionDiabetes mellitus is a major global health challenge, causing significant morbidity and mortality. Quercetin, a natural flavonoid, has potential antidiabetic and insulin-sensitizing effects. However, its clinical use is limited ...
Gold Nanoparticles: Diagnostic and Therapeutic Applications in Neurodegenerative Disorders [0.03%]
金纳米颗粒在神经退行性疾病诊断和治疗中的应用
Xin Hu,Jingxian Cheng,Ruri Yuan et al.
Xin Hu et al.
Neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and prion diseases, pose a significant and escalating health challenge in the context of an aging populat...
Microbiome-driven precision medicine: Advancing drug development with pharmacomicrobiomics [0.03%]
基于药用微生物组学的精准医疗：推动药物研发
Negar Ebadpour,Mohammad Abavisani,Amirhossein Sahebkar
Negar Ebadpour
Pharmacomicrobiomics investigates the complicated relationship between the gut microbiome and medications, highlighting how the microbiome affects drug absorption, metabolism, and overall treatment outcomes. The interaction between pharmace...
Revisiting VEGF/VEGFR-2 signaling as an anticancer target and its inhibitor discovery: Where are we and where should we go? [0.03%]
作为抗癌靶标的VEGF/VEGFR-2信号转导及其抑制剂的发现：我们已经取得了哪些进展？未来的方向是什么？
Sheng-Xin Yao,Yu-Jing Huang,Yue-Xi Zhang et al.
Sheng-Xin Yao et al.
Angiogenesis plays an important role in tumor growth and metastasis. Targeting tumor vascular endothelial cells to inhibit tumor angiogenesis and thus block tumor blood and nutrition supply is the current research focus on anti-tumor growth...