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Revisiting VEGF/VEGFR-2 signaling as an anticancer target and its inhibitor discovery: Where are we and where should we go?

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Angiogenesis plays an important role in tumor growth and metastasis. Targeting tumor vascular endothelial cells to inhibit tumor angiogenesis and thus block tumor blood and nutrition supply is the current research focus on anti-tumor growth and metastasis. Vas... ...