De-N-acetylated sialic acid is immunogenic and elicits antibodies that are protective against Neisseria meningitidis [0.03%]
脱N-乙酰神经氨酸具有免疫原性,并可诱发对脑膜炎奈瑟氏球菌具有保护作用的抗体
Gregory R Moe,Becca A Flitter,Jessica Y Ing et al.
Gregory R Moe et al.
Recently, we showed that monoclonal antibodies (mAbs) that are reactive with derivatives of polysialic acid containing de-N-acetylated neuraminic acid (Neu) residues are protective against N. meningitidis group B strains (Moe et al. 2005, I...