De-N-acetylated sialic acid is immunogenic and elicits antibodies that are protective against Neisseria meningitidis
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Recently, we showed that monoclonal antibodies (mAbs) that are reactive with derivatives of polysialic acid containing de-N-acetylated neuraminic acid (Neu) residues are protective against N. meningitidis group B strains (Moe et al. 2005, Infect Immun73: 2123;... ...