Effects of acetylation on human insulin structure, and dynamics at different temperatures: A molecular dynamics simulation study [0.03%]
乙酰化对人胰岛素结构和动力学的影响：分子动力学模拟研究
Reyhane Kamelnia,Bahram Goliaei,Faramarz Mehrnejad et al.
Reyhane Kamelnia et al.
Insulin was used as a model protein to investigate the effects of acetylation, a significant post-translational modification. Acetylation typically targets terminal and side-chain amine groups, which, in insulin, correspond to three specifi...
StaLAENet: A stacked LSTM-nested deep-autoencoder network for identification of antimicrobial resistance of nosocomial pathogens [0.03%]
基于堆叠LSTM嵌套深度自编码器网络的医院感染病原菌耐药表型鉴定模型STALEASENET
Mousumi Banerjee,Abhishake Lahiri,Sohom Basak et al.
Mousumi Banerjee et al.
As various technological innovations are assisting medical science in a considerable way, rendering a significant leap towards 'lab-to-land' delivery, in a similar vein, algorithm development and concomitant framework-based approaches help ...
Beyond morphology: Material alterations as inducible defenses in Daphnia longicephala [0.03%]
超出形态学的范畴：Daphnia longicephala中可诱发防御的材料改变
Wencke Krings,Sarah Becker,Greta Huttegger et al.
Wencke Krings et al.
The freshwater crustacean Daphnia is well known to adapt to the presence of predators by forming inducible defence structures. Large-scale morphological defensive traits are usually easily recognizable in most species. However, hidden mecha...
Interdependence of cytosolic and mitochondrial calcium dynamics in a hepatocyte cell due to obesity [0.03%]
肥胖引起的肝细胞胞浆和线粒体钙动态的相互依赖性关系
Vedika Mishra,Neeru Adlakha
Vedika Mishra
The intentional placement of mitochondria in close proximity to calcium ion (Ca2+) release sites enables the quick uptake of cytosolic Ca2+ and the close connection of calcium signaling with energy metabolism. Ca2+ dynamics have been thorou...
De novo hybrid genome assembly and analysis of Salmonella enterica serovar Kentucky of Indian origins [0.03%]
来自印度的新型杂合基因组组装和肯塔基沙门氏菌(Salmonella enterica)株系分析
Dhruv Das,A S Kakatkar,A V S S Narayana Rao et al.
Dhruv Das et al.
Salmonella enterica serovar Kentucky has emerged as a global human food-borne pathogen with a known phenotype of multidrug resistance. Whole-genome sequencing of the lab-isolated organism was performed to understand its genomic features usi...
Human tears as social chemo-signals in taming male aggression [0.03%]
人类眼泪通过化学信号作用平息男性攻击性行为的一种社交功能研究
Satish Suhas,Reeteka Sud,Shridhar J Utagi et al.
Satish Suhas et al.
The human brain is endlessly fascinating and complex. It is also highly plastic, shaped by numerous interacting factors, including sociocultural influences. Gender is one such factor, whose influence plays out on biological and cultural lev...
Review
Journal of biosciences. 2026:51:8. DOI: 2026
Enhancement of calcium responses by KIR current inactivation in medium spiny neurons [0.03%]
中脊椎神经元KIR电流失活增强钙反应
John Eric Steephen,Mithun Padmakumar,Rohit Manchanda
John Eric Steephen
Synaptic plasticity within cortico-striatal circuits critically influences learning and behavior, with the nucleus accumbens (NAc) serving as a key mediating structure. Within the NAc, medium spiny neurons (MSNs) are known to mediate input ...
How nettle (Urtica dioica) 'stings' Candida albicans by affecting its virulence factors [0.03%]
荨麻（Urtica dioica）通过影响其毒力因子来“刺痛”白色念珠菌
Dua&#x;a Riyad Husain Al-Saleh,Homa Darmani
Dua&#x;a Riyad Husain Al-Saleh
With increasing incidence of drug resistance and toxicity associated with current treatments, new alternatives are needed for Candida albicans infections. This study evaluated the potential of Urtica dioica aqueous extract and essential oil...
Surbhi Munda,S P Arun
Surbhi Munda
Consider the classic Ebbinghaus illusion in figure 1: the orange circle on the right seems bigger, even though both orange circles have the same size. Such size illusions occur in the real world too: in fact, a common dieting trick is to se...
Re-imagining T-cell receptor signaling: parallel paths may be key to discriminatory power [0.03%]
重新构思T细胞受体信号转导：平行路径可能是区分能力的关键
Akshay Tiwari,Narendra M Dixit
Akshay Tiwari
T-cells are important arms of our immune system and are central to our fight against pathogens and cancers (Baral et al. 2019a; Waldman et al. 2020). They recognize infected and cancerous cells and help destroy them while leaving uninfected...