Decoding the neural basis of olfactory dysfunction: a multimodal MRI study in CRS-OD [0.03%]
慢性鼻窦炎伴嗅觉障碍的神经影像学研究进展
C Zhang,Q Wang,C Jiang et al.
C Zhang et al.
Background: Chronic rhinosinusitis with olfactory dysfunction (CRS-OD) affects both peripheral and central olfactory pathways. Persistent olfactory loss may induce neuroplastic changes in brain regions involved in olfacto...
Targeted biologics for chronic rhinosinusitis with nasal polyps: efficacy and safety comparison of eight monoclonal antibodies via network meta-analysis [0.03%]
靶向生物制剂治疗鼻息肉型慢性鼻窦炎的疗效及安全性比较：基于8种单克隆抗体的网状meta分析
X Wang,P Ren,H He et al.
X Wang et al.
Background: Biologics targeting key type 2 inflammatory mediators (e.g., IL-4Rα, IgE, IL-5, TSLP) represent a novel therapeutic approach for chronic rhinosinusitis with nasal polyps (CRSwNP). This network meta-analysis (...
Response to the letter "Critical appraisal of methodological rigor in a systematic review on post-COVID-19 vaccination-associated olfactory dysfunction" [0.03%]
关于来信“系统评价新冠病毒疫苗后嗅觉障碍相关联的methodological rigor批判性评价”的回复
M Kawabata,E Mori,N Yanagi et al.
M Kawabata et al.
We appreciate the thoughtful comments by Dr. Gupta et al. (1) regarding our systematic review (2). Their commitment to this rare, but emerging clinical topic is welcome, and we would like to address the methodological points raised.
Digital intervention for smell training: a real-world study on engagement, adherence, and behavioural dynamics [0.03%]
数字干预在嗅觉训练中的应用：一项关于参与度、依从性和行为动态的真实世界研究
C Besevli,G Brianza,C Dawes et al.
C Besevli et al.
Background: Despite advances in digital health, many interventions fail, not due to technical shortcomings, but because they are not meaningfully adopted or sustained in everyday life. Understanding real-world engagement ...
Expanding the olfactory implant paradigm through recent advances in brain-computer interface technology [0.03%]
通过最近的脑机接口技术进展扩大嗅觉植入范式
E K Bhargava,M Arvaneh
E K Bhargava
The international opinion paper by Whitcroft et al. provides invaluable guidance for the emerging field of olfactory implants (1). While the authors thoroughly address clinical considerations and current technological approaches, we would l...
Upper and lower airways response to tezepelumab in asthma patients with / without comorbid nasal polyposis: a 6-months reallife perspective [0.03%]
特泽佩鲁玛治疗伴或不伴有鼻息肉的哮喘患者的上下呼吸道反应：6个月随访观察结果
M Caminati,A Mastrototaro,M Maule et al.
M Caminati et al.
Backgroud: The efficacy of tezepelumab in chronic rhinosinusitis with nasal polyps (CRSwNP) has been demonstrated in clinical trials, but real-world evidence remains limited. Our study investigated the trend of CRSwNP out...
Assessment of the extent of previous endoscopic sinus surgery using the ACCESS score in patients with chronic rhinosinusitis referred to tertiary care rhinologic clinics [0.03%]
三级鼻科门诊慢性鼻窦炎患者内镜鼻窦手术范围的评价：采用ACCESS评分标准研究
M Lazzeroni,R Hoven,E de Corso et al.
M Lazzeroni et al.
Background: Despite optimal medical and surgical therapy, many patients suffering from chronic rhinosinusitis (CRS) experience continuous inflammation for which revision surgery can be indicated. The present work was set ...
Integrated omics-based analysis reveals distinct microbial-metabolite interaction networks in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps in a Chinese population [0.03%]
整合组学分析揭示了中国鼻息肉患者中以嗜酸性粒细胞和非嗜酸性粒细胞为特征的慢性鼻窦炎中存在的不同微生物-代谢物相互作用网络
H Zhang,X Zi,X Li et al.
H Zhang et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition often classified into eosinophilic (Eos) and non-eosinophilic (nonEos) subtypes. While microbial dysbiosis and metabo...
K Resler,B R Castro,Z M Patel
K Resler
The COVID-19 pandemic brought attention to post-viral smell distortion, or parosmia, which is defined as a qualitative dysfunction resulting from distorted odor perception in the presence of an odorous medium (1). Very often, qualitative an...
Prevalence of ear complaints in patients with severe chronic rhinosinusitis with nasal polyps [0.03%]
重度过敏性真菌性鼻窦炎伴鼻息肉患者的耳部症状流行率
H B E Elzinga,J J Otten,R J L van der Lans et al.
H B E Elzinga et al.
Patients with chronic rhinosinusitis (CRS) commonly have ear complaints (ECs) (1). Reported prevalences in CRS-patients vary up to 61% (2, 3), and even higher (82%) in patients with nasal polyps (CRSwNP) with an indication for surgery (4). ...