Anthony J Hickey,Erik S Pena,Sara E Maloney Norcross
Anthony J Hickey
Dose accuracy and precision for pulmonary drug delivery have been core elements of therapy for asthma for 70 years. As the technology has developed, its application has spread to various diseases. For many inhaled products, solid-state chem...
Formulation of Bacteriophage for Inhalation to Treat Multidrug-Resistant Pulmonary Infections [0.03%]
用于治疗多重耐药性肺部感染的吸入型噬菌体配方
Vaibhav Pathak,Hak-Kim Chan,Qi Tony Zhou
Vaibhav Pathak
Rapid development of antibiotic resistance in pathogenic bacteria and a decline in the pharmaceutical development of new antibiotics are pushing the research community to explore alternative antimicrobials that can replace or complement ant...
Jiaqi Dong,Paul L Carpinone,Georgios Pyrgiotakis et al.
Jiaqi Dong et al.
Gold nanoparticles (AuNPs) exhibit unique size-dependent physiochemical properties that make them attractive for a wide range of applications. However, the large-scale availability of precision AuNPs has been minimal. Not only must the requ...
Aerosol Delivery of siRNA to the Lungs. Part 2: Nanocarrier-based Delivery Systems [0.03%]
肺部传递siRNA的研究第二部分：基于纳米载体的传递体系
Susanne R Youngren-Ortiz,Nishant S Gandhi,Laura España-Serrano et al.
Susanne R Youngren-Ortiz et al.
In this article, applications of engineered nanoparticles containing siRNA for inhalation delivery are reviewed and discussed. Diseases with identified protein malfunctions may be mitigated through the use of well-designed siRNA therapeutic...
Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery Systems [0.03%]
吸入性siRNA肺部给药（第一部分）：基因递送系统的理论基础
Susanne R Youngren-Ortiz,Nishant S Gandhi,Laura España-Serrano et al.
Susanne R Youngren-Ortiz et al.
This article reviews the pulmonary route of administration, aerosol delivery devices, characterization of pulmonary drug delivery systems, and discusses the rationale for inhaled delivery of siRNA. Diseases with known protein malfunctions m...