Error processing during online motor control depends on the response accuracy [0.03%]
在线电机控制中的错误处理依赖于响应准确性
Cécile Galléa,Jozina Bernhardina de Graaf,Jean Pailhous et al.
Cécile Galléa et al.
We investigated which brain areas show error-related activity during online motor control while errors occur independently from decision making. During motor tasks, error is a deviation from accuracy or correctness. The effect of the accura...
High-frequency stimulation of the dorsolateral periaqueductal gray and ventromedial hypothalamus fails to inhibit panic-like behaviour [0.03%]
对导水管周围灰质背侧外侧区和下丘脑腹内侧区的高频刺激不能抑制类似恐慌的行为反应
Lee Wei Lim,Arjan Blokland,Veerle Visser-Vandewalle et al.
Lee Wei Lim et al.
Electrical stimulation of the dorsolateral periaqueductal gray (dlPAG) and one of its target structures, the ventromedial hypothalamus (VMH), produces a typical behaviour in rats consisting of vigorous running and jumping which is known as ...
IL-6 mediated alterations on immobile behavior of rats in the forced swim test via ERK1/2 activation in specific brain regions [0.03%]
脑室内注射IL-6通过激活特定脑区的ERK1/2信号转导加重大鼠强迫游泳实验中的不动行为
Tung-Huan Wu,Chih-Hung Lin
Tung-Huan Wu
Interleukin-6 (IL-6), a proinflammatory cytokine, is well known as a mediator in early stage inflammatory immune reactions. In recent years, accumulating evidence has shown that IL-6 is concomitant with the occurrence of major depression. H...
Noam Y Miller,Robert Gerlai
Noam Y Miller
In many species, group cohesion may be the result of a compromise between opposing forces (e.g. predator avoidance and competition for food). However, little empirical data exists on the dynamics of group cohesion. We present moment-to-mome...
Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress [0.03%]
实验性脑创伤后Na+,K+-ATP酶活性损伤与空间学习障碍和氧化应激的关系
Frederico Diniz Lima,Mauren Assis Souza,Ana Flávia Furian et al.
Frederico Diniz Lima et al.
Traumatic brain injury (TBI) is a devastating disease that commonly causes persistent mental disturbances and cognitive deficits. Although studies indicate that oxidative stress and functional deficits occurring after TBI are interrelated e...
Anxiety-like behavior during nicotine withdrawal predict subsequent nicotine consumption in adolescent C57BL/6 mice [0.03%]
尼古丁戒断期间的类似焦虑的行为可以预测青春期C57BL/6小鼠随后的尼古丁消耗量
Alex C Manhães,Monique C S Guthierrez,Cláudio C Filgueiras et al.
Alex C Manhães et al.
We have previously demonstrated that anxiety-like behavior assessed in the elevated plus maze does not predict subsequent nicotine consumption in naïve adolescent mice. However, an association between anxiety and relapse to drug use has be...
Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks [0.03%]
中年载脂蛋白ε4替代替换型小鼠在多种空间记忆任务中出现的记忆缺失缺陷
Alexandra Bour,Jeannette Grootendorst,Elise Vogel et al.
Alexandra Bour et al.
Apolipoprotein (apo) E4, one of three human apoE (h-apoE) isoforms, has been identified as a major genetic risk factor for Alzheimer's disease and for cognitive deficits associated with aging. However, the biological mechanisms involving ap...
Knockout of the gene encoding the K(2P) channel KCNK7 does not alter volatile anesthetic sensitivity [0.03%]
敲除编码K(2P)通道KCNK7的基因不影响挥发性麻醉剂敏感性
C Spencer Yost,Irene Oh,Edmond I Eger nd et al.
C Spencer Yost et al.
The molecular site of action for volatile anesthetics remains unknown despite many years of study. Members of the K(2P) potassium channel family, whose currents are potentiated by volatile anesthetics have emerged as possible anesthetic tar...
Intranigral transplants of a GABAergic cell line produce long-term alleviation of established motor seizures [0.03%]
灌注GABA能细胞系的黑质内移植可长期缓解 established 意向性震颤
Claudia G Castillo,Soledad Mendoza-Trejo,Manuel B Aguilar et al.
Claudia G Castillo et al.
We have previously shown that intranigral transplants of immortalized GABAergic cells decrease the number of kainic acid-induced seizures [Castillo CG, Mendoza S, Freed WJ, Giordano M. Intranigral transplants of immortalized GABAergic cells...
Xuesheng Li,Yun Zhang,Xia Zhang
Xuesheng Li
We recently found that the interfering peptide Tat-3L4F is able not only to disrupt the protein-protein interaction of PTEN (phosphatase and tensin homologue deleted on chromosome 10) with the serotonin 5-HT2C receptor in the rat ventral te...