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Behavioural brain research. 2008 Nov 21;193(2):183-91. doi: 10.1016/j.bbr.2008.05.009 Q22.32025

IL-6 mediated alterations on immobile behavior of rats in the forced swim test via ERK1/2 activation in specific brain regions

脑室内注射IL-6通过激活特定脑区的ERK1/2信号转导加重大鼠强迫游泳实验中的不动行为 翻译改进

Tung-Huan Wu  1, Chih-Hung Lin

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  • 1 The Graduate Institute of Biological Science and Technology, Chung Hwa University of Medical Technology, Tainan County, Taiwan 717, Taiwan.
  • DOI: 10.1016/j.bbr.2008.05.009 PMID: 18573547

    摘要 Ai翻译

    Interleukin-6 (IL-6), a proinflammatory cytokine, is well known as a mediator in early stage inflammatory immune reactions. In recent years, accumulating evidence has shown that IL-6 is concomitant with the occurrence of major depression. However, the identification of the role of IL-6, as either an illness causation or immunotherapy in depression, remains to be further established. In the present study, 5-week old male Sprague-Dawley (SD) rats were used a... ...点击完成人机验证后继续浏览
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    期刊名:Behavioural brain research

    缩写:BEHAV BRAIN RES

    ISSN:0166-4328

    e-ISSN:1872-7549

    IF/分区:2.3/Q2

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    IL-6 mediated alterations on immobile behavior of rats in the forced swim test via ERK1/2 activation in specific brain regions