Di-, tetra-, and perhydropyrrolo[1,2- a]imidazoles: The Methods of Synthesis and Some Aspects of Application [0.03%]
二氢、四氢和全氢吡咯并[1,2-a]咪唑：合成方法及其应用方面的一些问题
Lesya M Saliyeva,Irina V Dyachenko,Ivanna Yu Danyliuk et al.
Lesya M Saliyeva et al.
The review summarizes and systematizes the literature data on the synthesis and some aspects of application of pyrrolo[1,2-a]imidazoles. Synthetic approaches are grouped according to the degree of saturation of the product pyrroloimidazole ...
Synthesis, structure, and biological activity of 4-hetaryl-2-pyrrolidones containing a pyrazole ring [0.03%]
含吡唑环的4-杂芳基-2-吡咯烷酮的合成、结构及生物活性研究
Natal&#x;ya V Gorodnicheva,Olga S Vasil&#x;eva,Evgeny S Ostroglyadov et al.
Natal&#x;ya V Gorodnicheva et al.
Single diastereomers of 4-hetaryl-2-pyrrolidone-3(5)-carbo- and 2-[4-hetaryl-2-pyrrolidon-1-yl]acetohydrazides were used in reactions with 2,4-pentanedione, providing (3R*,4S*)-3-, (4R*,5R*)-5-(3,5-dimethyl-1H-pyrazole-1-carbonyl)- and 1-[2...
The synthesis of ortho-stilbazoles (2-styrylpyridines) (microreview) [0.03%]
正-茋唑类化合物(2-乙烯基吡啶)的合成（微评述）
Saveliy P Sorokin,Oleg V Ershov
Saveliy P Sorokin
This microreview compiles methods for the synthesis of ortho-stilbazoles (2-styrylpyridines) described in the literature in 2017-2022. Depending on the synthons from which the target structure is formed, four main synthetic approaches can b...
Synthesis and antiproliferative activity characterization of new imidazothiazolotriazine oxindolylidene derivatives containing various substituents in the oxindole ring [0.03%]
含不同取代基的吲哚嗪亚胺唑噻唑三嗪衍生物的合成及其抗增殖活性研究
Alexei N Izmest&#x;ev,Angelina N Kravchenko,Galina A Gazieva
Alexei N Izmest&#x;ev
Condensation of 1,3-diethyltetrahydroimidazo[4,5-е]thiazolo[3,2-b][1,2,4]triazine-2,7-dione with isatins followed by framework rearrangement in the thiazolotriazine moiety was used to synthesize two new series of oxindolylidenetetrahydroim...
Synthesis of isomeric 4-(N-methyltetrazolylamino)-2-phenyl-4 H-thiopyrano[2,3- b]quinoline-3-carbaldehydes and 4-hydroxy-2-phenyl-4 H-thiopyrano[2,3- b]quinoline-3-carbaldehyde based on tandem thiol-Michael and (aza)-Morita-Baylis-Hillman reactions and an in vitro study of the activity of the obtained compounds against influenza virus [0.03%]
基于串联硫醇迈克尔和（氮） Morita-Baylis-Hillman 反应合成异构体 4-（N-甲基四唑氨基）-2-苯基-4H-噻吡兰[2,3-b]喹啉-3-甲醛以及 4-羟基-2-苯基-4H-噻吡兰[2,3-b]喹啉-3-甲醛并研究所得化合物对流感病毒的体外活性
Andrey V Khramchikhin,Mariya А Skryl&#x;nikova,Yuliya N Pavlyukova et al.
Andrey V Khramchikhin et al.
3-{[(1-Methyl-1H-tetrazol-5-yl)imino]methyl}quinoline-2-thiol and 3-{[(2-methyl-2H-tetrazol-5-yl)imino]methyl}quinoline-2-thiol were synthesized. The sequence of the thiol-Michael reaction and the (aza)-Morita-Baylis-Hillman reaction yielde...
Expanding the chemical space of 3(5)-functionalized 1,2,4-triazoles [0.03%]
含3(5)位官能团的1,2,4-三唑类化合物化学空间的扩展
Dmytro M Khomenko,Roman O Doroshchuk,Yulia M Ohorodnik et al.
Dmytro M Khomenko et al.
An efficient approach to the gram-scale synthesis of 3(5)-substituted, 1,3- and 1,5-disubstituted 1,2,4-triazole-derived building blocks is described. The key synthetic precursors - 1,2,4-triazole-3(5)-carboxylates (20 examples, 35-89% yiel...
Yulia Yu Belyakova,Peter S Radulov
Yulia Yu Belyakova
A summary of approaches developed for the synthesis of stable cyclic aza-peroxides is presented. © Springer Science+Business Media, LLC, part of Springe...
Novel Approach to the Synthesis of 3-amino-4-arylpyridin-2(1 H)-one Derivatives [0.03%]
3-氨基-4-芳基吡啶并酮衍生物的新合成方法研究进展
Vladislav Yu Shuvalov,Sergei А Chernenko,Anton L Shatsauskas et al.
Vladislav Yu Shuvalov et al.
The reaction of 4-arylidene-2-phenyloxazol-5(4H)-ones with enamines of ethyl acetoacetate gave 4-aryl-2-methyl-6-oxo-5-[(phenylcarbonyl)amino]-1,4,5,6-tetrahydropyridine-3-carboxylic acid esters, which, when heated with phosphorus oxychlori...
Synthesis, structure, and antiviral properties of novel 2-adamantyl-5-aryl-2 H-tetrazoles [0.03%]
新型2-金刚烷基-5-芳基-2H-四氮唑的合成、结构及其抗病毒活性研究
Olga V Mikolaichuk,Vladimir V Zarubaev,Anna А Muryleva et al.
Olga V Mikolaichuk et al.
The reaction of 5-aryl-NH-tetrazoles with adamantan-1-ol in concentrated sulfuric acid proceeds regioselectively with the formation of the corresponding 2-adamantyl-5-aryl-2H-tetrazoles. Nitration of these compounds leads to 2-(adamantan-1-...
Pyrimido[1,2- a]benzimidazoles: synthesis and perspective of their pharmacological use [0.03%]
并四苯并咪唑类化合物的合成及其药用前景展望
Victor V Fedotov,Vladimir L Rusinov,Evgeny N Ulomsky et al.
Victor V Fedotov et al.
The review presents data on the synthesis as well as studies of biological activity of new derivatives of pyrimido[1,2-a]benzimidazoles published over the last decade. The bibliography of the review includes 136 sources. ...