Synthesis of isomeric 4-(N-methyltetrazolylamino)-2-phenyl-4 H-thiopyrano[2,3- b]quinoline-3-carbaldehydes and 4-hydroxy-2-phenyl-4 H-thiopyrano[2,3- b]quinoline-3-carbaldehyde based on tandem thiol-Michael and (aza)-Morita-Baylis-Hillman reactions and an in vitro study of the activity of the obtained compounds against influenza virus
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3-{[(1-Methyl-1H-tetrazol-5-yl)imino]methyl}quinoline-2-thiol and 3-{[(2-methyl-2H-tetrazol-5-yl)imino]methyl}quinoline-2-thiol were synthesized. The sequence of the thiol-Michael reaction and the (aza)-Morita-Baylis-Hillman reaction yielded 4-[(1-methyl-1H-te... ...
