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Arkajit Guha,Ruma Banerjee Arkajit Guha
The enzyme is susceptible to oxidative inactivation and is repaired by methionine synthase reductase (MTRR) in the presence of NADPH and S-adenosylmethionine (AdoMet).
Raunak Raunak,Roopshali Rakshit,Aayush Bahl et al. Raunak Raunak et al.
The recombinant protein exhibited distinctive kinetic properties, characterized by higher substrate affinity yet increased susceptibility to oxidative inactivation compared to its M. tuberculosis counterpart.
Jonas Thomsen,Signe Lett,Helle J Martens et al. Jonas Thomsen et al.
With an iron content of 2 g/kg dry peat, oxidative inactivation of enzymes is an important factor to take into account....A high inactivation constant of 125.91 x10-3 h-1 was found for the used saccharification conditions, but the addition of catalase alleviated the oxidative inactivation and increased the glucose yield with 60% in peat pretreated at 180 °C.
Frances Jourd&#x;heuil,Clinton Mathai,Le Gia Cat Pham et al. Frances Jourd&#x;heuil et al.
In addition, the ectopic expression of cytoglobin in cultured cells limited the inhibitory effect of H2O2 on glycolysis and reversed the oxidative inactivation of the glycolytic enzyme GAPDH. Cytoglobin facilitated the reduction of the thiol-based H2O2 sensor Hyper7 after H2O2 challenge.
Juan Sebastián Reyes,Eduardo Fuentes-Lemus,Angélica Fierro et al. Juan Sebastián Reyes et al.
In the present work we report the oxidative inactivation of hG6PDH mediated by peroxyl radicals (ROO=) generated by AAPH (2,2'-azobis(2-methylpropionamidine) dihydrochloride) thermolysis. hG6PDH (46.4 μM, monomers) was incubated at 37 ºC with 10 or 100 mM AAPH.
Yufei Chen,Yuan Lin,Jin Hong et al. Yufei Chen et al.
Conclusions: OroA inhibits platelet activation, thrombus formation and myocardial injury via reversing SHP-2 oxidative inactivation thereby attenuating collagen-induced GPVI signaling.
Luuk Loeff,Alena Kroupova,Igor Asanović et al. Luuk Loeff et al.
The metazoan tRNA ligase complex (tRNA-LC) has essential roles in tRNA biogenesis and unfolded protein response. Its catalytic subunit RTCB contains a conserved active-site cysteine that is susceptible to metal ion-induced oxidative inactiv...
Tatiana Staroňová,Jitka Holčáková,Petr Voňka et al. Tatiana Staroňová et al.
Galectin-1 (Gal-1) displays unique sensitivity to oxidative inactivation which appears critical in regulating its spatial and temporal activity. The two physicochemical states, i.e. monomer-dimer equilibrium and redox states, are related to Gal-1 varying functionality.
Junichi Fujii Junichi Fujii
On the other hand, oxidative inactivation of mitochondrial aconitase increases citrate, which is then recruited to synthesize fatty acids in the cytoplasm.
Guilherme Vilela-Alves,Rita R Manuel,Aldino Viegas et al. Guilherme Vilela-Alves et al.
Metal-dependent formate dehydrogenases are very promising targets for enzyme optimization and design of bio-inspired catalysts for CO2 reduction, towards innovative strategies for climate change mitigation. For effective application of thes...
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