sFlt-1/PlGF Ratio in the Prediction of Preeclampsia in Pregnant Women With Diabetic Kidney Disease [0.03%]
糖尿病肾病孕妇HELLP综合征与子痫预测标志物(sFlt-1/PlGF比值)的变化特征研究
Jakub Kornacki,Ewa Wender-Ozegowska,Daniel Boroń et al.
Jakub Kornacki et al.
Objectives: The objective of the study is to evaluate the potential role of the sFlt-1/PlGF ratio in predicting preeclampsia (PE) in pregnant women with diabetic kidney disease (DKD) during the second and third trimesters of pregnancy. Study Design: This study included 102 patients with DKD.
Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia [0.03%]
两例I型糖原贮积病合并子痫前期患者的胎盘病变
V Laufs,A Hasenburg,M A Busch et al.
V Laufs et al.
We report on two primipara with GSD Ia who both developed preeclampsia and whose newborns were small for gestational age. Both placentas showed sonomorphological and macroscopical abnormalities.
Preventing Preeclampsia With Low-Dose Aspirin: A Systematic Review of Efficacy Across Diverse Populations [0.03%]
小剂量阿司匹林预防子痫前期的疗效多样性系统评价研究
Rebecca George,Zaheeruddin Sayed,Hamesh Gundala Raja et al.
Rebecca George et al.
This systematic review evaluates the efficacy of low-dose aspirin (LDA) in preventing preeclampsia in high-risk pregnancies. A comprehensive search of recent randomized controlled trials was conducted, focusing on studies published within the last five years....Findings indicate that LDA can reduce preeclampsia risk, particularly in specific subgroups such as non-Hispanic white women, but its efficacy is influenced by factors such as aspirin resistance, ethnicity, and biomarker levels....This review underscores the need for future research to address gaps in aspirin efficacy across different populations and to explore biomarker-driven strategies for preeclampsia prevention....Keywords: aspirin resistance; biomarkers; high-risk pregnancies; low-dose aspirin; personalized medicine; preeclampsia prevention; randomized controlled trials. Copyright © 2025, George et al.
Summer Sherburne Hawkins
Summer Sherburne Hawkins
Although evidence supporting the benefits of low-dose aspirin for the prevention of preeclampsia has been building for nearly four decades, many women with high-risk pregnancies still do not receive this potentially life-saving medication.
CD34 in preeclampsia: The role of endothelial cell pyroptosis and regulation by melatonin via melatonin membrane receptor 1 [0.03%]
子痫前期中CD34的作用:内皮细胞焦亡及褪黑素通过膜受体1调节作用
Xiaoyu Feng,Bo Chen,Yi Yang et al.
Xiaoyu Feng et al.
Preeclampsia (PE) is a serious clinical complication of pregnancy, whose etiology is remains poorly understood but is strongly linked to endothelial dysfunction. In this study, we have confirmed that low expression of CD34 is closely relate...
A low maternal sFlt-1 before 11 weeks is associated with a greater risk of early preeclampsia [0.03%]
妊娠11周前低母体sFlt-1与早期子痫前期的风险增加有关
Emmanuel Bujold,Charlotte K Ekelund,Berit Woetmann Pedersen et al.
Emmanuel Bujold et al.
Single cell RNA-sequencing reveals BHLHE40 and NDRG1 as key regulatory molecules modulating the trophoblastic senescence in preeclampsia [0.03%]
单细胞RNA测序揭示BHLHE40和NDRG1是调节子痫前期滋养层衰老的关键调控分子
Yang Zhang,Jie Chu,Zhicheng Yu et al.
Yang Zhang et al.
Introduction: Preeclampsia (PE) is a severe obstetric complication characterized by trophoblastic dysfunction and compromised placental development. Cellular senescence has been notably reported in PE trophoblasts, which ...
Stillbirth is associated with postpartum severe maternal morbidity compared to gestational age matched and term livebirths [0.03%]
与同孕周及足月活产儿相比,死胎与产后严重产妇并发症相关
Dante Varotsis,Jordan Beacham,Julie Gomez et al.
Dante Varotsis et al.
ACOG recommends close postpartum follow up for patients at increased risk for severe maternal morbidity and mortality, such as those suffering from preeclampsia or hypertension.
Assessing the risk of preeclampsia/eclampsia in Mississippi black women with chronic kidney disease using electronic health records [0.03%]
利用电子健康记录评估慢性肾脏病对密西西比州黑人妇女妊娠期高血压疾病的风险
John S Clemmer,Kaua A Campos,Seth T Lirette et al.
John S Clemmer et al.
Future research aims to investigate genetic factors causing renal and endothelial changes to better understand and address the causes of higher rates of preeclampsia in black women with CKD.
Insufficient expression of VTN promotes the development of early-onset severe preeclampsia through the HEY1/autophagy signaling pathway [0.03%]
VTN表达下调通过HEY1/自噬信号通路促进早期重度子痫前期发病发展
Gonghua Qi,Yanmin Gong,Yi Li et al.
Gonghua Qi et al.
Introduction: Early-onset severe preeclampsia (eosPE) is a serious pregnancy complication that affects maternal and fetal health....Keywords: Autophagy; Early-onset severe preeclampsia (eosPE); HEY1; VTN. Copyright © 2025 Elsevier Ltd. All rights reserved.
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