Tomas Uher,Dominika Stastna,Ingrid Menkyova et al.
Tomas Uher et al.
Objective: The impact of SARS-CoV-2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord ...
Two distinct trajectories of brain volume loss in myotonic dystrophy type 1 via machine learning [0.03%]
利用机器学习发现肌迟缓性营养不良I型中大脑体积减小的两种不同的发展轨迹
Tomoki Imokawa,Hiroyuki Maki,Daichi Sone et al.
Tomoki Imokawa et al.
Myotonic dystrophy Type 1 is a disorder that affects multiple systems, including the muscles and the CNS. Previous studies have primarily used voxel-based morphometry to examine areas of brain volume reduction and their correlation with sym...
Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis [0.03%]
多发性硬化症中血浆CHI3L1与脑体积丢失及星形胶质细胞活化相关
Venla Ahola,Maija Saraste,Marjo Nylund et al.
Venla Ahola et al.
Background: Multiple sclerosis (MS) progression independent of relapses is driven by brain innate immune cell activation. The aim of this study was to evaluate the association between chitinase-3-like protein 1 (CHI3L1), ...
Short- and long-term effects of early versus delayed treatment with ocrelizumab on cerebellar volume loss in patients with RMS and PPMS [0.03%]
早期使用奥克雷珠单抗与晚期使用相比对RMSS和PPMS患者的小脑体积损失的短期和长期影响
Douglas L Arnold,Shannon Kolind,Haz-Edine Assemlal et al.
Douglas L Arnold et al.
Background: The cerebellum is a functionally and anatomically complex structure, which, in multiple sclerosis (MS), is affected by focal white/gray matter lesions and by secondary neurodegeneration of afferent/efferent co...
Brain Volume Loss After Stereotactic Laser Interstitial Thermal Therapy in Patients With Temporal Lobe Epilepsy [0.03%]
放射外科手术治疗颞叶癫痫患者的脑体积丢失状况研究
Sebastian Johannes Müller,Eya Khadhraoui,Olga Kukhlenko et al.
Sebastian Johannes Müller et al.
Background and purpose: Temporal lobe epilepsy is the most common form of focal epilepsy. MR-guided laser interstitial thermal therapy (LITT) of the amygdalohippocampal complex has become an established therapy option in ...
Preoperative brain volume loss is associated with postoperative delirium in advanced heart failure patients supported by left ventricular assist device [0.03%]
左心室辅助装置支持的终末期心力衰竭患者术前脑体积损失与术后谵妄有关
Iván Murrieta-Álvarez,Jacob P Scioscia,José M Benítez-Salazar et al.
Iván Murrieta-Álvarez et al.
Delirium is a common neurological complication in patients with advanced heart failure (ADHF) following left ventricular assist device (LVAD) implantation, significantly impacting recovery. This study aimed to analyze non-contrast computed ...
Stability of locus coeruleus cell counts despite volume loss in cognitively impaired aged rhesus macaques [0.03%]
认知障碍恒河猴黑素浓集层神经元数量不受大脑体积损失影响
Kelsey E McDermott,Carol A Barnes
Kelsey E McDermott
The locus coeruleus (LC) is a brainstem nucleus that provides the primary source of noradrenaline (NA) in the nervous system and optimizes behavioral performance in mammals. In humans, the LC shows Alzheimer's disease (AD)-like pathology at...
Patients with relapsing-remitting multiple sclerosis show accelerated whole brain volume and thalamic volume loss early in disease [0.03%]
复发缓解型多发性硬化症患者早期疾病全脑体积和丘脑体积损失加速
Roland Opfer,Matthias Schwab,Sabine Bangoura et al.
Roland Opfer et al.
Background: The aim of this study was to investigate the dynamics of annual whole brain volume loss (BVL/year) and annual thalamic volume loss (ThalaVL/year) in patients with relapsing-remitting multiple sclerosis (PwRRMS...
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2-3 gliomas [0.03%]
颅内放射治疗后的脑容量损失：质子疗法与光子疗法治疗WHO II-III级胶质瘤的对照研究
Melissa M Gardner,Sebastian F Winter,Franziska Stahl et al.
Melissa M Gardner et al.
Purpose: Radiation therapy (RT) is an integral treatment component in patients with glioma but associated with neurotoxicity. Proton RT (PRT), as compared with photon RT (XRT), reduces excess radiation to nontarget tissue...
Brain volume loss in relapsing multiple sclerosis: indirect treatment comparisons of available disease-modifying therapies [0.03%]
复发性多发性硬化症脑体积损失：现有疾病修正疗法的间接比较治疗研究
Robert Zivadinov,Alexander J Keenan,Hoa H Le et al.
Robert Zivadinov et al.
Background: Brain volume loss (BVL) has been identified as a predictor of disability progression in relapsing multiple sclerosis (RMS). As many available disease-modifying treatments (DMTs) have shown an effect on slowing...
Meta-Analysis
BMC neurology. 2024 Oct 8;24(1):378. DOI:10.1186/s12883-024-03888-6 2024
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