Changing genes, cells and networks to reprogram the brain after stroke [0.03%]
脑卒中后的基因、细胞和网络的改变以重新编程大脑
Wenlu Li,Paul George,Matine M Azadian et al.
Wenlu Li et al.
Important advances have been made in reperfusion therapies for acute ischemic stroke. However, a majority of patients are either ineligible for or do not respond to treatments and continue to have considerable functional deficits. Stroke re...
Brain-targeted mild hypothermia ameliorates ischemic brain injury and promotes stroke recovery in aged mice [0.03%]
大脑靶向轻度低温缓解老年小鼠缺血性脑损伤并促进卒中恢复
Junxuan Lyu,Liqiang Liu,Mengyuan Guo et al.
Junxuan Lyu et al.
Therapeutic hypothermia represents a highly promising approach for alleviating ischemic brain injury. However, the majority of preclinical studies predominantly rely on reperfusion-based models using young animals, which poorly reflect the ...
Exercise improves stair climbing performance after stroke: A systematic review of randomized trials with meta-analysis [0.03%]
运动改善卒中后上下楼梯功能：随机对照试验的系统综述及荟萃分析
Lucas Rodrigues Nascimento,Amanda Marcele de Souza Oliveira,Grazyelle Maria Silva Pereira de Moraes et al.
Lucas Rodrigues Nascimento et al.
Background: Exercises have been used to improve outcomes after stroke. Objective: To examine the effects of planned, structured, and re...
George D Fulk,Karen J Klingman,Sandra A Billinger et al.
George D Fulk et al.
Study objectives: People with stroke are susceptible to developing sleep disorders, which may negatively impact recovery. Little is known about sleep health (SH) broadly and its impact on recovery after stroke. The purpos...
Acute, not delayed, treatment of aflibercept enhances vessel density in post-ischemic brain and promotes long-term stroke recovery in obese mice [0.03%]
阿伐斯汀急性而非延迟治疗增强缺血脑血管密度并促进肥胖小鼠长期卒中恢复
Hyunwoo Ju,Joseph Minker,Ina Pavlova et al.
Hyunwoo Ju et al.
Vascular comorbidities complicate stroke pathophysiology, worsen outcomes, and delay recovery. Obesity, in particular, significantly increases stroke-induced brain edema, a fatal complication during infarction, which leads to worsened long-...
A Habit-Forming Exercise Approach Promotes Positive Exercise Beliefs and Behaviours: A Survey of People After Stroke [0.03%]
一种养成习惯的锻炼方法可促进中风后人群积极的运动态度和行为：一项调查研究
Ingrid Lin,Catherine Dean,Joanne Glinsky et al.
Ingrid Lin et al.
Background and aims: LiFE is a habit-forming functional exercise program that is not widely used in stroke but could facilitate exercise and support long-term physical activity. The purpose of this study was to determine,...
Navigating Complexity: Lessons Learned from Co-Designing a Care Transition Intervention for People with Stroke [0.03%]
应对复杂性：卒中患者护理过渡干预共设计的教训
Sebastian Lindblom,Charlotte Ytterberg,Ann Charlotte Laska et al.
Sebastian Lindblom et al.
Introduction: Participatory, emergent, and reflective approaches are needed in research on person-centred integrated care. This paper describes and explores the process of developing a complex care transition intervention...
Harnessing Mirror Neurons: Improving Balance and Quality of Life After a Stroke [0.03%]
利用镜像神经元改善卒中后的平衡和生活质量
Preeti Sharma,Zeeshan Ali,Sudhan S George
Preeti Sharma
Background: Action observation engages brain motor networks, and action imitation helps neurological and musculoskeletal problem patients improve motor learning and functional recovery. In this study, we focused on identi...
Environmental enrichment: a neurostimulatory approach to aging and ischemic stroke recovery and rehabilitation [0.03%]
环境丰富刺激：一种神经刺激疗法在抗衰老和中风恢复中的应用
Sijina Kinattingara Parambath,Navami Krishna,Rajanikant Golgodu Krishnamurthy
Sijina Kinattingara Parambath
Environmental enrichment (EE) represents a robust experimental framework exploring the intricate interplay between genes and the environment in shaping brain development and function. EE is recognized as a non-invasive intervention, easily ...
Repair-associated macrophages increase after early-phase microglia attenuation to promote ischemic stroke recovery [0.03%]
与修复相关的巨噬细胞在早期阶段的微胶质细胞减弱后增加以促进缺血性中风恢复
Xiaotao Zhang,Huaming Li,Yichen Gu et al.
Xiaotao Zhang et al.
Ischemic stroke recovery involves dynamic interactions between the central nervous system and infiltrating immune cells. Peripheral immune cells compete with resident microglia for spatial niches in the brain, but how modulating this balanc...
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