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Molecular medicine reports. 2019 Oct;20(4):3617-3624. doi: 10.3892/mmr.2019.10607 Q23.52025

MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo

微RNA-155通过上调调节性T细胞抑制白癜风CD8+T淋巴细胞增殖 翻译改进

Mingfen Lv  1, Zhengjun Li  1, Jingjing Liu  2, Fan Lin  2, Qianwen Zhang  3, Zhiming Li  2, Yi Wang  4, Keyu Wang  1, Yunsheng Xu  2

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作者单位

  • 1 Department of Dermatology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China.
  • 2 Department of Dermatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
  • 3 Department of Dermatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. ChinaDepartment of Dermatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
  • 4 Department of Dermatology, Jinan Central Hospital, Jinan, Shandong 250013, P.R. China.

    • DOI: 10.3892/mmr.2019.10607 PMID: 31485649

    摘要 Ai翻译

    It has been reported that loss and degradation of epidermal melanocytes is closely associated with the pathogenesis of vitiligo. In addition, CD8+ T and regulatory T (Treg) cells serve an important role during these two processes. MicroRNA‑155 (miR‑155) is known to contribute to the pathogenesis of vitiligo; however, the mechanism by which miR‑155 regulates the development of vitiligo remains unclear. In the present study, naïve T and CD8+ T cells were... ...点击完成人机验证后继续浏览
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    期刊名：Molecular medicine reports

    缩写：MOL MED REP

    ISSN：1791-2997

    e-ISSN：1791-3004

    IF/分区：3.5/Q2

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    MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo