Here, we present a facile one-step Sonogashira dispersion polymerization affording monodisperse conjugated polymer particles bearing accessible acetylene moieties on the surface. These acetylene groups are easily functionalized with biological recognition motifs using thiol-yne click chemistry. The resulting functional particles are applied as fluorescent probes for imaging of activated endothelial cells, which take up the particles via receptor mediated endocytosis.
Chemical communications (Cambridge, England). 2015 Jun 7;51(45):9358-61. doi: 10.1039/c4cc10092a Q24.22025
RGD-decorated conjugated polymer particles as fluorescent biomedical probes prepared by Sonogashira dispersion polymerization
通过Sonogashira分散聚合制备带有RGD的共轭聚合物粒子作为荧光生物医学探针 翻译改进
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DOI: 10.1039/c4cc10092a PMID: 25958787
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